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Hemojuvelin

Summary

UniProt ID

Q8N7M5

Gene Symbol

Hfe2
Hjv
Rgmc

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q8N7M5
The Human Metabolome Database: HMDBP14615
Re-Glyco: Q8N7M5

Annotation

Keyword

Autocatalytic cleavage
Cell membrane
Disulfide bond
GPI-anchor
Phosphoprotein
Reference proteome
Signal

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
BMP receptor complex
HFE-transferrin receptor complex
extracellular space
plasma membrane
plasma membrane protein complex
cell surface
basolateral plasma membrane
side of membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 10** entries
GO Term
positive regulation of transcription by RNA polymerase II
activin receptor signaling pathway
negative regulation of transcription by RNA polymerase II
intracellular iron ion homeostasis
BMP signaling pathway
negative regulation of BMP signaling pathway
multicellular organismal-level iron ion homeostasis
protein autoprocessing
transcription by RNA polymerase II
cellular response to BMP stimulus

Displaying **all 4** entries
GO Term
signaling receptor binding
transferrin receptor binding
coreceptor activity
BMP binding

Annotation information from UniProt.

Sequence

MGDRGRSPSLRSPHGSPPTLSTLTLLLLLCGQAHSQCKILRCNAEYVSFTLSLRGGGSPDTPRGGGRGGPASGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTASPPARGPALPGAGPAPLTPDPCDYEARFSRLHGRTPGFLHCASFGDPHVRSFHNHFHTCRVQGAWPLLDNDFLFVQATSSPVASGANATTIRKITIIFKNMQECIDQKVYQAEVDNLPAAFEDGSVNGGDRPGGSSLSIQTANLGSHVEIRAAYIGTTIIVRQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFDVSVSGDPNFTVAAQSALDDARVFLTDLENLHLFPVDAGPPLSPATCLVRLLSVLFVLWFCIQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites