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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Vesicular glutamate transporter 3
Summary
- UniProt ID
- Q8NDX2
- Gene Symbol
-
- SLC17A8
- VGLUT3
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q8NDX2
- The Human Metabolome Database
- HMDBP03945
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Chloride channel
- Cytoplasmic vesicle
- Disease variant
- Glycoprotein
- Hearing
- Neurotransmitter transport
- Non-syndromic deafness
- Phosphate transport
- Reference proteome
- Sodium transport
- Symport
- Synaptosome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of glutamate uptake involved in transmission of nerve impulse |
| neurotransmitter loading into synaptic vesicle |
| sodium-dependent phosphate transport |
| neural retina development |
| GO Term |
|---|
| axon terminus |
| excitatory synapse |
| synaptic vesicle membrane |
| chloride channel complex |
| perikaryon |
| multivesicular body |
| apical dendrite |
| basal dendrite |
| glial limiting end-foot |
| pericellular basket |
Sequence
MPFKAFDTFKEKILKPGKEGVKNAVGDSLGILQRKIDGTTEEEDNIELNEEGRPVQTSRPSPPLCDCHCCGLPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIMTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWSSVFYIYGMFGIIWYMFWLLQAYECPAAHPTISNEEKTYIETSIGEGANVVSLSKFSTPWKRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRQILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTRHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQEWADPENLSEEKCGIIDQDELAEEIELNHESFASPKKKMSYGATSQNCEVQKKEWKGQRGATLDEEELTSYQNEERNFSTIS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 106 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25) | Homo sapiens |
| Organic anion transporters | Homo sapiens |
| Sensory processing of sound by inner hair cells of the cochlea | Homo sapiens |
