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E3 ubiquitin-protein ligase COP1

Summary

UniProt ID

Q8NHY2

Gene Symbol

COP1
RFWD2
RNF200

Gene ID

64326

Organism

Homo sapiens (human)

External Links

GlyGen: Q8NHY2
PubChem: Q8NHY2
Re-Glyco: Q8NHY2

Annotation

Keyword

3D-structure
Alternative splicing
Coiled coil
Cytoplasm
Nucleus
Proteomics identification
Reference proteome
Repeat
Transferase
Ubl conjugation
Ubl conjugation pathway
WD repeat
Zinc-finger

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
nucleoplasm
cytosol
nuclear speck
Cul4A-RING E3 ubiquitin ligase complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 4** entries
GO Term
protein ubiquitination
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
response to ionizing radiation

Displaying **all 3** entries
GO Term
metal ion binding
ubiquitin-protein transferase activity
ubiquitin protein ligase activity

Annotation information from UniProt.

Sequence

MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKVLELV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites