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IQ motif and SEC7 domain-containing protein 1

Summary

UniProt ID

Q8R0S2

Gene Symbol

Iqsec1
Kiaa0763

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q8R0S2
The O-GlcNAc Database: Q8R0S2
RaftProt: Q8R0S2
O-GlcNAcAtlas: Q8R0S2

Annotation

Keyword

Alternative splicing
Coiled coil
Cytoplasm
Cytoplasmic vesicle
Guanine-nucleotide releasing factor
Lipid-binding
Nucleus
Phosphoprotein
Reference proteome
Synapse

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
regulation of postsynaptic neurotransmitter receptor internalization
positive regulation of focal adhesion disassembly
actin cytoskeleton organization
positive regulation of keratinocyte migration
positive regulation of synapse assembly
postsynaptic modulation of chemical synaptic transmission
dendritic spine development
regulation of ARF protein signal transduction

Displaying **all 5** entries
GO Term
synaptic vesicle
Schaffer collateral - CA1 synapse
postsynaptic density, intracellular component
nucleus
glutamatergic synapse

Displaying **all 3** entries
GO Term
lipid binding
protein kinase binding
guanyl-nucleotide exchange factor activity

Annotation information from UniProt.

Sequence

MWCLHCNSERTQSLLELELDSGVEGEAPSSETGTSLDSPSAYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGPGPQQRTRRPRLQHSTSVLRKQAEEEAIKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQLGALVPSECGDLSDPALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASDTARARDTEPKPGLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSDRSDRSSLKRQSAYERSLGGQQGSPKHGPHGGPPKGLPREEPELRPRPPRPLESHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFTDDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYASGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVEFQPFQPPQPPVLCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites