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Integrin beta-3

Summary

UniProt ID

Q8R2H2

Gene Symbol

Itgb3

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q8R2H2

Annotation

Keyword

Calcium
Cell adhesion
Cell junction
Cell membrane
Cell projection
Disulfide bond
EGF-like domain
Glycoprotein
Integrin
Magnesium
Metal-binding
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

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GO Term
cellular response to insulin-like growth factor stimulus
negative regulation of lipid storage
positive regulation of cell-matrix adhesion
cell-matrix adhesion
viral entry into host cell
cell-substrate junction assembly
integrin-mediated signaling pathway
response to activity
cell-substrate adhesion
cellular response to platelet-derived growth factor stimulus

Displaying entries **11 - 20** of 26 in total

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GO Term
filopodium membrane
microvillus membrane
nucleoplasm
nucleus
plasma membrane
cell-cell junction
focal adhesion
integrin complex
external side of plasma membrane
cell surface

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GO Term
enzyme binding
metal ion binding
vascular endothelial growth factor receptor 2 binding
cell adhesion molecule binding
extracellular matrix binding
fibrinogen binding
C-X3-C chemokine binding
insulin-like growth factor I binding
identical protein binding
fibronectin binding

Annotation information from UniProt.

Sequence

MRTRRPGQLWATLLALGALAGVVVGESNICTTRGVNSCQQCLAVSPVCAWCSDESLPQNSPRCNLKKNLLKDKCSPESIEFPVSEAQILEALPLSSKGSGDSAQITQVSPQRIALRLRPDDSKIFSLQVRQVEDYPVDIYYLMDLSFSMKDDLSSIQTLGTKLASQMRKLTSNLRIGFGAFVDKPVSPYMFISPPQAIKNPCYTMKSTCLPMFGYKHVLTLTDQVTRFNDEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVLPNDGRCHIGPDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVSLYQNYSELIPGTTVGVLSDDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCVGLKIGDTVSFSIEAKVRGCPQQKEQSFTIKPVGFKDSLTVQVTFDCDCDCQAFAQPLSPRCNNGNGTFECGVCRCDQGWLGSMCECSEEDYRPSQQEECSPKEGQPICSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNGLLCSGRGNCECGSCVCVQPGSYGDTCEKCPTCPDACSFKKDCVECKKFNRGKLHEENNCNRFCRDDIELVKELTDTGKNAVNCTYKNEDDCVVRFQYYEDSSGRAVLYVVEEPECPKGPDILVVLLSVMGAILLIGLATLLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
345	N-linked (GlcNAc...) asparagine	UniProt
396	N-linked (GlcNAc...) asparagine	UniProt
477	N-linked (GlcNAc...) asparagine	UniProt
584	N-linked (GlcNAc...) asparagine	UniProt
679	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 14** of 14 in total

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Pathway Name	Organism
Syndecan interactions	Rattus norvegicus
TGF-beta receptor signaling activates SMADs	Rattus norvegicus
VEGFA-VEGFR2 Pathway	Rattus norvegicus
p130Cas linkage to MAPK signaling for integrins	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements