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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Replication protein A 70 kDa DNA-binding subunit
Summary
- UniProt ID
- Q8VEE4
- Gene Symbol
-
- Rpa1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ADP-ribosylation
- Acetylation
- DNA recombination
- DNA repair
- DNA replication
- DNA-binding
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| telomere maintenance via telomerase |
| in utero embryonic development |
| DNA damage response |
| positive regulation of cell population proliferation |
| GO Term |
|---|
| nucleoplasm |
| nucleus |
| site of DNA damage |
| lateral element |
| DNA replication factor A complex |
| condensed chromosome |
| PML body |
| condensed nuclear chromosome |
| male germ cell nucleus |
| GO Term |
|---|
| damaged DNA binding |
| single-stranded DNA binding |
| single-stranded telomeric DNA binding |
| chromatin binding |
| metal ion binding |
Sequence
MVGHLSEGAIEVMIQQENTSIKPILQVINIRPISTGNRSPRYRLLMSDGLNTLSSFMLATQLNTLVEGGQLASNCVCQVHKFIVNTLKDGRKVVVLMDLEVMKSAEDVGLKIGNPVPYNEGYGQQQQQQQQQQQQAVPSPASAATPPASKPQPQNGSLGMGSTAAKAYGASKPFGKPAGTGLLQPSGGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSLELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGALKIANKQFSAVKNDYEMTFNNETSVLPCEDGHHLPTVQFDFTGIGDLESKAKDALVDIIGICKSYEDSIKITVKSNNREVAKRNIYLMDMSGKVVTTTLWGEDADKFDGSRQPVMAIKGARVSDFGGRSLSVLSSSTVIVNPDIPEAYKLRGWFDSEGQALDGVSISDHRSGGAGGGNTNWKTLHEAKSENLGQGDKADYFSTVAAVVFLRKENCMYQACPTQDCNKKVIDQQNGLYRCEKCDREFPNFKYRMILSANIADFQENQWVTCFQESAEAILGQNTMYLGELKEKNEQAFEEVFQNANFRSFTFRIRVKLETYNDESRIKATVMDVKPVDFRDYGRRLIANIRKNM
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 145 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of ATR in response to replication stress | Mus musculus |
| Activation of the pre-replicative complex | Mus musculus |
| Dual Incision in GG-NER | Mus musculus |
| Dual incision in TC-NER | Mus musculus |
| Fanconi Anemia Pathway | Mus musculus |
| Formation of Incision Complex in GG-NER | Mus musculus |
| G2/M DNA damage checkpoint | Mus musculus |
| Gap-filling DNA repair synthesis and ligation in GG-NER | Mus musculus |
| Gap-filling DNA repair synthesis and ligation in TC-NER | Mus musculus |
| HDR through Homologous Recombination (HRR) | Mus musculus |
