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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Inactive heparanase-2
Summary
- UniProt ID
- Q8WWQ2
- Gene Symbol
-
- HPSE2
- HPA2
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q8WWQ2
- The Human Metabolome Database
- HMDBP11785
Annotation
- Keyword
-
- Alternative splicing
- Extracellular matrix
- Glycoprotein
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| cell population proliferation |
| positive regulation of cell population proliferation |
| extracellular matrix organization |
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| extracellular matrix |
| GO Term |
|---|
| heparanase activity |
| heparan sulfate proteoglycan binding |
Sequence
MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTLILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREKAAQMHLVLLKEQFSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| HS-GAG degradation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111414 | trichohepatoenteric syndrome | |
| DOID:0111415 | trichohepatoenteric syndrome 1 | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:1040 | chronic lymphocytic leukemia | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1074 | kidney failure | |
| DOID:10763 | hypertension | |
| DOID:10825 | essential hypertension | |
| DOID:10844 | Japanese encephalitis |
