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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor 1-A
Summary
- UniProt ID
- Q90Z00
- Gene Symbol
-
- fgfr1a
- fgfr1
- Organism
- Danio rerio (zebrafish)
External Links
- PubChem
- Q90Z00
- The Human Metabolome Database
- HMDBP12141
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| pectoral fin development |
| negative regulation of endodermal cell fate specification |
| GO Term |
|---|
| cytosol |
| nucleus |
| plasma membrane |
| cytoplasmic vesicle |
| receptor complex |
| GO Term |
|---|
| fibroblast growth factor receptor activity |
| fibroblast growth factor binding |
| ATP binding |
| heparin binding |
Sequence
MKMMMIMKTTLLLISVLLTQALQSQGRPAIQDEAPAEPTSYTLDSGEKLELSCKAKEDTQKVTWTKDLVPLVDGEHTRLRNDQMEIEKVEPTDSGLYACFAQGLNSNHTEYFNISVTDEEDEVDSSSEEAKLSNDQNLPMAPVWAQPDKMEKKLHAVPASKTVKFRCQANGNPTPTLKWLKNGKEFKRDQRIGGFKVREHMWTIIMESVVPSDRGNYTCLVENRHGSINHTYQLDVVERSPHRPILQAGLPANRTAVVGSDVEFECKVFSDPQPHIQWLKHIEVNGSRYGPDGLPYVRALKTAGVNTTDKEMEVLQIRNVSLEDAGEYTCLAGNSIGHSHHSAWLTVYKAVPPTQLPNQTYLEVLIYCVGFFLICVMVGTAVLAKMHSSAKKSDFNSQLAVHKLAKSIPLRRQVTVSVDSSSSMHSGGMLVRPSRLSSSGSPMLSGVSEYELPQDPRWEVQRDRLVLGKPLGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDLDRTLSMTSNQEYLDLSVSLDQFSPNFPDTRSSTCSSGEDSVFSHDAGADEPCLPKFPPHPNRGVAFKKR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 107 | N-linked (GlcNAc...) asparagine |
|
||
| 113 | N-linked (GlcNAc...) asparagine |
|
||
| 216 | N-linked (GlcNAc...) asparagine |
|
||
| 229 | N-linked (GlcNAc...) asparagine |
|
||
| 253 | N-linked (GlcNAc...) asparagine |
|
||
| 285 | N-linked (GlcNAc...) asparagine |
|
||
| 306 | N-linked (GlcNAc...) asparagine |
|
||
| 319 | N-linked (GlcNAc...) asparagine |
|
||
| 358 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream signaling of activated FGFR1 | Danio rerio |
| FGFR1b ligand binding and activation | Danio rerio |
| FGFR1c and Klotho ligand binding and activation | Danio rerio |
| FGFR1c ligand binding and activation | Danio rerio |
| FRS-mediated FGFR1 signaling | Danio rerio |
| Negative regulation of FGFR1 signaling | Danio rerio |
| PI-3K cascade:FGFR1 | Danio rerio |
| PI3K/AKT Signaling | Danio rerio |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Danio rerio |
| Phospholipase C-mediated cascade: FGFR1 | Danio rerio |
