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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Alpha-2,8-sialyltransferase 8B
Summary
- UniProt ID
- Q92186
- Gene Symbol
-
- ST8SIA2
- SIAT8B
- STX
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q92186
- The Human Metabolome Database
- HMDBP14212
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Nucleotide-binding
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| extracellular region |
| Golgi apparatus |
| plasma membrane |
| early endosome |
| perinuclear region of cytoplasm |
| recycling endosome |
| GO Term |
|---|
| nucleotide binding |
| alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity |
| sialic acid binding |
Sequence
MQLQFRSWMLAALTLLVVFLIFADISEIEEEIGNSGGRGTIRSAVNSLHSKSNRAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHNQTLSLRIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDSTMNVSQNLYELLPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKHHVNVRTAYPSLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALKSLHEQGALKLTVGQCDGAT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 60 | N-linked (GlcNAc...) asparagine |
|
||
| 72 | N-linked (GlcNAc...) asparagine |
|
||
| 89 | N-linked (GlcNAc...) asparagine |
|
||
| 134 | N-linked (GlcNAc...) asparagine |
|
||
| 219 | N-linked (GlcNAc...) asparagine |
|
||
| 234 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| N-Glycan antennae elongation | Homo sapiens |
| NCAM1 interactions | Homo sapiens |
| Sialic acid metabolism | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:6726 | fibrillary astrocytoma | |
| DOID:0060180 | colitis | |
| DOID:0060189 | ileitis | |
| DOID:0060190 | ileocolitis | |
| DOID:100 | intestinal infectious disease | |
| DOID:12385 | shigellosis | |
| DOID:12554 | hemolytic-uremic syndrome | |
| DOID:12849 | autistic disorder | |
| DOID:1324 | lung cancer |
