CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

Summary
UniProt ID
Q92187
Gene Symbol
  • ST8SIA4
  • PST
  • PST1
  • SIAT8D
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0012443
GlyGen
Q92187
The Human Metabolome Database
HMDBP14324
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Disulfide bond
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Reference proteome
  • Secreted
  • Signal-anchor
  • Transmembrane helix
Gene Ontology (GO)
Sequence
MRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHNVEGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCVKQ
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
50 N-linked (GlcNAc...) asparagine
74 N-linked (GlcNAc...) asparagine
119 N-linked (GlcNAc...) asparagine
185
204 N-linked (GlcNAc...) asparagine
219 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
NCAM1 interactions Homo sapiens
Sialic acid metabolism Homo sapiens
Disease
Displaying entries 1 - 10 of 135 in total
DO ID Disease Name Source
DOID:0050127 sinusitis
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0050635 alternating hemiplegia of childhood
DOID:0050741 alcohol dependence
DOID:0050759 myotonic dystrophy type 2
DOID:0050766 choreaacanthocytosis
DOID:0050865 tongue squamous cell carcinoma
DOID:0060262 gallbladder disease
DOID:0060891 Parkinson's disease 19A
DOID:0060895 Parkinson's disease 4

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024