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cGMP-dependent 3',5'-cyclic phosphodiesterase

Summary

UniProt ID

Q922S4

Gene Symbol

Pde2a

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q922S4
The O-GlcNAc Database: Q922S4

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cytoplasm
Direct protein sequencing
Hydrolase
Magnesium
Metal-binding
Mitochondrion inner membrane
Mitochondrion outer membrane
Myristate
Palmitate
Phosphoprotein
Reference proteome
Repeat
Zinc
cAMP
cGMP-binding

Gene Ontology (GO)

Displaying entries **11 - 20** of 28 in total

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GO Term
negative regulation of transcription by RNA polymerase II
regulation of mitochondrion organization
negative regulation of oxidative phosphorylation
regulation of nitric oxide mediated signal transduction
negative regulation of cGMP-mediated signaling
cAMP-mediated signaling
cGMP-mediated signaling
regulation of cAMP-mediated signaling
negative regulation of cAMP-mediated signaling
establishment of endothelial barrier

Displaying entries **11 - 16** of 16 in total

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GO Term
synaptic membrane
hippocampal mossy fiber
mitochondrion
mitochondrial inner membrane
mitochondrial matrix
cytosol

Displaying **all 9** entries
GO Term
cAMP binding
cGMP binding
3',5'-cyclic-GMP phosphodiesterase activity
GAF domain binding
metal ion binding
identical protein binding
protein homodimerization activity
3',5'-cyclic-AMP phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

Annotation information from UniProt.

Sequence

MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPQPCADSLQDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIREAVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPVNGCCSLEG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites