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cGMP-dependent 3',5'-cyclic phosphodiesterase

Summary

UniProt ID

Q922S4

Gene Symbol

Pde2a

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q922S4
The O-GlcNAc Database: Q922S4

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cytoplasm
Direct protein sequencing
Hydrolase
Magnesium
Metal-binding
Mitochondrion inner membrane
Mitochondrion outer membrane
Myristate
Palmitate
Phosphoprotein
Reference proteome
Repeat
Zinc
cAMP
cGMP-binding

Gene Ontology (GO)

Displaying entries **21 - 28** of 28 in total

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GO Term
aorta development
negative regulation of vascular permeability
positive regulation of vascular permeability
cellular response to lipopolysaccharide
cGMP catabolic process
negative regulation of transcription by RNA polymerase II
regulation of mitochondrion organization
negative regulation of oxidative phosphorylation

Displaying entries **11 - 16** of 16 in total

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GO Term
mitochondrial matrix
cytosol
endoplasmic reticulum
mitochondrial outer membrane
presynaptic membrane
perinuclear region of cytoplasm

Displaying **all 9** entries
GO Term
cAMP binding
cGMP binding
3',5'-cyclic-GMP phosphodiesterase activity
GAF domain binding
metal ion binding
identical protein binding
protein homodimerization activity
3',5'-cyclic-AMP phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

Annotation information from UniProt.

Sequence

MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPQPCADSLQDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIREAVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPVNGCCSLEG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites