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Acid sphingomyelinase-like phosphodiesterase 3b

Summary

UniProt ID

Q92485

Gene Symbol

ASML3B
ASMLPD
SMPDL3B

Gene ID

27293

Organism

Homo sapiens (human)

External Links

RaftProt: Q92485
Re-Glyco: Q92485

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
GPI-anchor
Glycosidase
Inflammatory response
Innate immunity
Lipid degradation
Metal-binding
Reference proteome
Secreted
Signal
Zinc

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
extracellular space
plasma membrane
side of membrane
extracellular exosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 6** entries
GO Term
negative regulation of toll-like receptor signaling pathway
membrane lipid catabolic process
inflammatory response
innate immune response
negative regulation of inflammatory response
sphingomyelin catabolic process

Displaying **all 4** entries
GO Term
hydrolase activity, acting on glycosyl bonds
zinc ion binding
sphingomyelin phosphodiesterase activity
phosphoric diester hydrolase activity

Annotation information from UniProt.

Sequence

MRLLAWLIFLANWGGARAEPGKFWHIADLHLDPDYKVSKDPFQVCPSAGSQPVPDAGPWGDYLCDSPWALINSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKVYAALGNHDFHPKNQFPAGSNNIYNQIAELWKPWLSNESIALFKKGAFYCEKLPGPSGAGRIVVLNTNLYYTSNALTADMADPGQQFQWLEDVLTDASKAGDMVYIVGHVPPGFFEKTQNKAWFREGFNEKYLKVVRKHHRVIAGQFFGHHHTDSFRMLYDDAGVPISAMFITPGVTPWKTTLPGVVNGANNPAIRVFEYDRATLSLKDMVTYFMNLSQANAQGTPRWELEYQLTEAYGVPDASAHSMHTVLDRIAGDQSTLQRYYVYNSVSYSAGVCDEACSMQHVCAMRQVDIDAYTTCLYASGTTPVPQLPLLLMALLGLCTLVL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites