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MIRAGE
Discoidin domain-containing receptor tyrosine kinase B

Summary
UniProt ID
Q95ZV7
Gene Symbol
  • F11D5.3
  • ddr-2
  • svh-4
Gene ID
180622
Organism
Caenorhabditis elegans
PubChem
Q95ZV7
Re-Glyco
Q95ZV7
Annotation
Keyword
  • ATP-binding
  • Alternative splicing
  • Cell membrane
  • Cell projection
  • Disulfide bond
  • Glycoprotein
  • Neurogenesis
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
Gene Ontology (GO)
Displaying all 4 entries
GO Term
plasma membrane
axon
receptor complex
perikaryon
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MKLLLYLFGVTFHSNTVVALELRECSHQLGMSNRKIRDEQISASSSFDLQSTGPQHARAHQESGSGAWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDLQSGISYHDFSYDGNLANSPHLTGGIGKLYDGEVGKNNVFVNHHKWVGWRRKRNGNVKLAFEFSELRNISGILIHTSNEFKKSAKAFSSATVLFSINGKDFSDTIVHFNNPEDTESEVPRWIRIPVNNRIAKVAKIRLNFGTDSDWLFISEVNFESNHTNIELLNDDVVIPDSVSYFSVTEHDDGTSMFAFIIFFFMFLIVAVIILTVLYRKREYRVKASSPSPNAKREILLTIDGNTIKHHVSPSTYQMARDNLQNALIEKMPMSPIISDYAEPDISVCSDVTANTPLLYGIDGPYDTQKRSNPLSSMVKYSDYGEVYCTTLPEIARDKLICVSRIGQGEFGEVDLCQLENRKVAVKKLHGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSYILKNPTIQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKVEGKFVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENVHLHLQSLVHTSPHIHF
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
141 N-linked (GlcNAc...) asparagine
167 N-linked (GlcNAc...) asparagine
264 N-linked (GlcNAc...) asparagine
353 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 10 entries
Pathway Name Organism
Downstream signal transduction Caenorhabditis elegans
FLT3 Signaling Caenorhabditis elegans
Integrin cell surface interactions Caenorhabditis elegans
PI3K/AKT Signaling Caenorhabditis elegans
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Caenorhabditis elegans
RAF/MAP kinase cascade Caenorhabditis elegans
Regulation of KIT signaling Caenorhabditis elegans
Signaling by PDGF Caenorhabditis elegans
Signaling by SCF-KIT Caenorhabditis elegans
VEGFA-VEGFR2 Pathway Caenorhabditis elegans
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025