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Ubiquitin thioesterase otulin
Summary
- UniProt ID
- Q96BN8
- Gene Symbol
-
- FAM105B
- OTULIN
- Gene ID
- 90268
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Angiogenesis
- Cytoplasm
- Disease variant
- Innate immunity
- Phosphoprotein
- Reference proteome
- Thiol protease
- Ubl conjugation
- Ubl conjugation pathway
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| LUBAC complex |
| cytoplasm |
| cytosol |
| GO Term |
|---|
| cysteine-type deubiquitinase activity |
| cysteine-type peptidase activity |
Sequence
MSRGTMPQPEAWPGASCAETPAREAAATARDGGKAAASGQPRPEMQCPAEHEEDMYRAADEIEKEKELLIHERGASEPRLSVAPEMDIMDYCKKEWRGNTQKATCMKMGYEEVSQKFTSIRRVRGDNYCALRATLFQAMSQAVGLPPWLQDPELMLLPEKLISKYNWIKQWKLGLKFDGKNEDLVDKIKESLTLLRKKWAGLAEMRTAEARQIACDELFTNEAEEYSLYEAVKFLMLNRAIELYNDKEKGKEVPFFSVLLFARDTSNDPGQLLRNHLNQVGHTGGLEQVEMFLLAYAVRHTIQVYRLSKYNTEEFITVYPTDPPKDWPVVTLIAEDDRHYNIPVRVCEETSL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 321 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of TNFR1 signaling | Homo sapiens |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080163 | otulipenia | |
| DOID:612 | primary immunodeficiency disease |
