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AP-2 complex subunit mu

Summary

UniProt ID

Q96CW1

Gene Symbol

AP2M1
CLAPM1
KIAA0109

Organism

Homo sapiens (human)

External Links

GlyGen: Q96CW1
PubChem: Q96CW1
The Human Metabolome Database: HMDBP14128
RaftProt: Q96CW1

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Coated pit
Disease variant
Endocytosis
Epilepsy
Intellectual disability
Lipid-binding
Phosphoprotein
Protein transport
Reference proteome

Gene Ontology (GO)

Displaying entries **11 - 12** of 12 in total

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GO Term
clathrin-dependent endocytosis
negative regulation of protein localization to plasma membrane

Displaying entries **1 - 10** of 15 in total

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GO Term
postsynapse
cytoplasmic side of plasma membrane
endocytic vesicle membrane
clathrin-coated endocytic vesicle membrane
endolysosome membrane
extrinsic component of presynaptic endocytic zone membrane
lysosomal membrane
clathrin-coated pit
AP-2 adaptor complex
extracellular exosome

Displaying **all 6** entries
GO Term
lipid binding
transmembrane transporter binding
low-density lipoprotein particle receptor binding
disordered domain specific binding
clathrin adaptor activity
signal sequence binding

Annotation information from UniProt.

Sequence

MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
412			G80920RR	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 16 in total

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Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Homo sapiens
Clathrin-mediated endocytosis	Homo sapiens
EPH-ephrin mediated repulsion of cells	Homo sapiens
Formation of annular gap junctions	Homo sapiens
Gap junction degradation	Homo sapiens
LDL clearance	Homo sapiens
MHC class II antigen presentation	Homo sapiens
Nef Mediated CD4 Down-regulation	Homo sapiens
Nef Mediated CD8 Down-regulation	Homo sapiens
Nef mediated downregulation of CD28 cell surface expression	Homo sapiens