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MIRAGE

Dynein regulatory complex protein 1

Summary

UniProt ID: Q96MC2
Gene Symbol: DRC1 C2orf39 CCDC164
Gene ID: 92749
Organism: Homo sapiens (human)

External Links

The O-GlcNAc Database: Q96MC2
RaftProt: Q96MC2
Re-Glyco: Q96MC2

Annotation

Keyword: 3D-structure Coiled coil Cytoskeleton Disease variant Flagellum Primary ciliary dyskinesia Proteomics identification Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
regulation of cilium movement	IBA	GO_REF
single fertilization
determination of left/right symmetry
heart development
cilium-dependent cell motility	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

epithelial cilium movement involved in extracellular fluid movement [inference]

mucociliary clearance

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

organelle assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

protein-containing complex assembly [inference]

axonemal dynein complex assembly

organelle assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

sperm flagellum assembly

fertilization [inference]

single fertilization

multicellular organismal process [inference]

system process [inference]

respiratory system process [inference]

mucociliary clearance

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

developmental process [inference]

developmental process involved in reproduction [inference]

sperm flagellum assembly

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

animal organ development [inference]

heart development

localization [inference]

establishment of localization [inference]

transport [inference]

extracellular transport [inference]

epithelial cilium movement involved in extracellular fluid movement [inference]

mucociliary clearance

microtubule-based transport [inference]

epithelial cilium movement involved in extracellular fluid movement [inference]

mucociliary clearance

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of microtubule-based process [inference]

regulation of microtubule-based movement [inference]

regulation of cilium movement

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
extracellular region
cytosol	IEA	GO_REF
axonemal dynein complex	IEA	GO_REF
axoneme	ISS	GO_REF
axoneme	NAS	PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex [inference]

axonemal dynein complex

catalytic complex [inference]

dynein complex [inference]

axonemal dynein complex

cellular anatomical structure [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MNPPGSLEALDPNVDEHLSTQILAPSVHSDNSQERIQARRLRIAARLEARRREALGEYLDGKKESEEDQSKSYKQKEESRLKLAKLLLCGTELVTNIQVAIDIREIHRRVEEEEIKRQRIEKLENEVKTSQDKFDEITSKWEEGKQKRIPQELWEMLNTQQLHCAGLLEDKNKLISELQQELKTKDDQYVKDLKKQSDDICLLLERMEEQVKNVMKTFREELYNIEKAFEVERQELLASNKKKWEQALQAHNAKELEYLNNRMKKVEDYEKQLNRQRIWDCEEYNMIKIKLEQDVQILEQQLQQRKAIYQLNQEKLEYNLQVLKKRDEESTVIKSQQKRKINRLHDILNNLRSKYAKQIKQFQEENQSLTSDYKRLVMQFKELQKAMRHFALIDDEKFWEIWLMNEEEAKDLIARAFDVDRIIHTHHLGLPWAAPDFWFLNNVGPISQQPQKSATQIVEEMLMRSEEEEAEEAAAEPESYLDLPKQISEKTTKRILMLLCDESGFLIESKLLSLLLPLEQNECYLLRLDAIFSALGIESEDDLYKLVNFFLKYRAHRLSSSLQIKPCSQASMEKASMEETSTRSELELAEQTEMEGEKEESLVEGEKEEEEETPPSPWVIHPNDVLKILEAFVMGLKKPRDSRAPLRVQKNVRDNSKDSEYWQALTTVIPSSKQNLWDALYTALEKYHLVLTQRAKLLLENSSLEQQNTELQALLQQYLNSKINSELQVPPTQVLRVPTK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
601		29237092	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0070579	spermatogenic failure 80	Alliance of Genome Resources
DOID:0110596	primary ciliary dyskinesia 21	Alliance of Genome Resources

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026