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MIRAGE
ATP-dependent zinc metalloprotease YME1L1
Summary
- UniProt ID
- Q96TA2
- Gene Symbol
-
- FTSH1
- UNQ1868/PRO4304
- YME1L
- YME1L1
- Gene ID
- 10730
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Disease variant
- Metal-binding
- Metalloprotease
- Mitochondrion inner membrane
- Reference proteome
- Transmembrane helix
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| mitochondrial inner membrane |
| membrane |
| nuclear body |
| GO Term |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| ATP binding |
| ATP hydrolysis activity |
| ATP-dependent peptidase activity |
Sequence
MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFSDFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSCLYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 28 |
|
|||
| 115 |
|
|||
| 161 |
|
|||
| 220 |
|
|||
| 222 |
|
|||
| 335 |
|
|||
| 566 |
|
|||
| 592 |
|
|
||
| 641 |
|
|||
| 680 |
|
G62765YT
G49108TO
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cellular response to mitochondrial stress | Homo sapiens |
| Mitochondrial protein degradation | Homo sapiens |
| Processing of SMDT1 | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111436 | optic atrophy 11 |
