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Forkhead box protein P3

Summary

UniProt ID

Q99JB6

Gene Symbol

Foxp3

Gene ID

20371

Organism

Mus musculus (house mouse)

External Links

PubChem: Q99JB6
The O-GlcNAc Database: Q99JB6
Re-Glyco: Q99JB6

Annotation

Keyword

3D-structure
Acetylation
Activator
Cytoplasm
DNA-binding
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repressor
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
nucleus
cytoplasm
nucleoplasm
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 72 in total

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GO Term
negative regulation of T-helper 17 cell differentiation
negative regulation of transcription by RNA polymerase II
DNA-templated transcription
regulation of transcription by RNA polymerase II
response to lipopolysaccharide
gene expression
negative regulation of cytokine production
myeloid cell homeostasis
T cell mediated immunity
tolerance induction

Displaying entries **1 - 10** of 12 in total

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GO Term
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
transcription corepressor activity
identical protein binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
histone acetyltransferase binding

Annotation information from UniProt.

Sequence

MPNPRPAKPMAPSLALGPSPGVLPSWKTAPKGSELLGTRGSGGPFQGRDLRSGAHTSSSLNPLPPSQLQLPTVPLVMVAPSGARLGPSPHLQALLQDRPHFMHQLSTVDAHAQTPVLQVRPLDNPAMISLPPPSAATGVFSLKARPGLPPGINVASLEWVSREPALLCTFPRSGTPRKDSNLLAAPQGSYPLLANGVCKWPGCEKVFEEPEEFLKHCQADHLLDEKGKAQCLLQREVVQSLEQQLELEKEKLGAMQAHLAGKMALAKAPSVASMDKSSCCIVATSTQGSVLPAWSAPREAPDGGLFAVRRHLWGSHGNSSFPEFFHNMDYFKYHNMRPPFTYATLIRWAILEAPERQRTLNEIYHWFTRMFAYFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDEFEFRKKRSQRPNKCSNPCP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	GlyTouCan ID	Source
33	G49108TO	The O-GlcNAc Database
38	G49108TO	The O-GlcNAc Database
57	G49108TO	The O-GlcNAc Database
58	G49108TO	The O-GlcNAc Database
59	G49108TO	The O-GlcNAc Database
72	G49108TO	The O-GlcNAc Database
270	G49108TO	The O-GlcNAc Database
273	G49108TO	The O-GlcNAc Database
285	G49108TO	The O-GlcNAc Database
286	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	Mus musculus

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0090110	immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome	Alliance of Genome Resources
DOID:9169	Wiskott-Aldrich syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements