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Double-stranded RNA-specific adenosine deaminase

Summary

UniProt ID

Q99MU3

Gene Symbol

Adar

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q99MU3
PubChem: Q99MU3
The O-GlcNAc Database: Q99MU3

Annotation

Keyword

Alternative splicing
Antiviral defense
Cytoplasm
DNA-binding
Hydrolase
Innate immunity
Isopeptide bond
Metal-binding
Methylation
Nucleus
Phosphoprotein
RNA-binding
RNA-mediated gene silencing
Reference proteome
Repeat
Transcription regulation
Ubl conjugation
Zinc
mRNA processing

Gene Ontology (GO)

Displaying entries **1 - 10** of 25 in total

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GO Term
osteoblast differentiation
hematopoietic progenitor cell differentiation
somatic diversification of immune receptors via somatic mutation
apoptotic process
erythrocyte differentiation
innate immune response
hematopoietic stem cell homeostasis
hepatocyte apoptotic process
negative regulation of hepatocyte apoptotic process
definitive hemopoiesis

Displaying **all 5** entries
GO Term
nucleus
nucleolus
cytoplasm
nuclear speck
supraspliceosomal complex

Displaying **all 5** entries
GO Term
metal ion binding
left-handed Z-DNA binding
double-stranded RNA binding
double-stranded RNA adenosine deaminase activity
tRNA-specific adenosine deaminase activity

Annotation information from UniProt.

Sequence

MSQGFRGPTGVFPHQTQSYLDPSHEHSKWRYPQPQGPESYPRSFQLQQIEFLKGRLPEAPLIGIQTQSLPPFLPGHWPRFPGPPAQDRQLEIWEFPRSVTLRNQGFHIGPPLPPPHSRGTPWRGADGLCSHFRELSISQSPEQKVLNRLEELGEGKATTAHVLARELRIPKRDINRILYSLEKKGKLHRGRGKPPLWSLVPLSQAWTQPPGVVNPDSCIQEFPRGEPGLDSEDGDPASDLEGPSEPLDMAEIKEKICDYLFNVSNSSALNLAKNIGLTKARDVTSVLIDLERQGDVYRQGATPPIWYLTDKKRERLQMKRSTHSAPAPTPTAVPEATRSPSFPACHPPPAGASSSVAASKRVENGQEPAIKHESRHEARPGPMRLRPHAYHNGPSRAGYVASENGQWATDDIPDNLNSIHTAPGEFRAIMEMPSFYSPTLPRCSPYKKLTECQLKNPVSGLLEYAQFTSQTCDFNLIEQSGPSHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAVKAMAILLREAKAKDSGQPEDLSHCPMEEDSEKPAEAQAPSSSATSLFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHDPKFQYCVAVGAQTFPPVSAPSKKVAKQMAAEEAMKALQEEAASSADDQSGGANTDSLDESMAPNKIRRIGELVRYLNTNPVGGLLEYARSHGFAAEFKLIDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQDAADAALRVLIGESEKAEQLGFAEVTPVTGASLRRTMLLLSRSPDAHPKTLPLSGSTFHDQIAMLSHRCFNALTNSFQPSLLGRKILAAIIMKRDPEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNHHTAKNSIFELARGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAVESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPVYLKSVTLGYLFSQGHLTRAICCRVTRDGKAFEDGLRYPFIVNHPKVGRVSVYDSKRQSGKTKETSVNWCMADGYDLEILDGTRGTVDGPGKELSRVSKKNIFLQFKKLCSFRARRDLLQLSYGEAKKAARDYDLAKNYFKKSLRDMGYGNWISKPQEEKNFYLCPVPND

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites