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Zona pellucida sperm-binding protein 2

Summary

UniProt ID: Q9BH10
Gene Symbol: ZP2 ZPA
Gene ID: 280963
Organism: Bos taurus (domestic cattle)

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Zona pellucida sperm-binding protein 2

Re-Glyco

Q9BH10

Annotation

Keyword: Cell membrane Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Extracellular matrix Fertilization Glycoprotein Receptor Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
binding of sperm to zona pellucida	ISS	PMID
binding of sperm to zona pellucida	IBA	GO_REF
prevention of polyspermy	ISS	PMID
prevention of polyspermy	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell recognition [inference]

cell-cell recognition [inference]

sperm-egg recognition [inference]

binding of sperm to zona pellucida

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of reproductive process [inference]

negative regulation of fertilization [inference]

prevention of polyspermy

regulation of reproductive process [inference]

regulation of fertilization [inference]

negative regulation of fertilization [inference]

prevention of polyspermy

negative regulation of reproductive process [inference]

negative regulation of fertilization [inference]

prevention of polyspermy

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
multivesicular body	ISS	GO_REF
endoplasmic reticulum	ISS	GO_REF
plasma membrane	ISS	GO_REF
plasma membrane	IEA	GO_REF
extracellular matrix	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix

specialized extracellular matrix [inference]

egg coat

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

Displaying **all 3** entries
GO Term	Evidence Code	Reference
acrosin binding	IBA	GO_REF
structural constituent of egg coat	ISS	GO_REF
structural constituent of egg coat	IBA	GO_REF

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent [inference]

structural constituent of egg coat

binding [inference]

protein binding [inference]

enzyme binding [inference]

acrosin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MACRQRGDSGRPSSWFRADWRSFFLSFTLLTSVNSIDVNQLDPAFPGTVTCYENRMVVEFKRTLGNKIQHASVVDSLGLKMLNCTYVLDPEKLTLKAPYESCTKRVLGQHQMTITFMNDNTAHRQKTVLYHVSCPVMQAGRHDQHSGSTICSKDFMSFTFHFFPGLADDTAGPKPQMGWTVTVGDGERAQNLTLQEALTQGYNLLIENQKMSIQVLFHATGVTHYSQGNSHLYMVPLKLTHVSPGQTIILSSRLICASDPVTCNATHMTLTIPEFPGKLKSVSFENKNIAVNQLHNSGIVMEIANGLRLHFSKTLLKTKFSEKCLPYQFYLSSLKLTFYTQLETVSMVIYPECVCESTVSIVSGELCTQDGFMDVEVYRHQTKPALNLDTLRVGDSSCQPTIKAPFQGLVKFHIPLNGCGTRHKFENGKVIYENEIHALWADLPPSTISRDSEFRMTVRCYYSSSNMLINTNVESLPPPVASVKPGPLALTLQTYPDNSYLQPYGDKDYPVVRYLRQPIYLEVRVLNRTDPNIKLVLDDCWATSTMDPASLPQWNIIVDGCEYNLDNHRTTFHPVGSSVAYPNHYQRFAVKTFAFVSEDPAFSHLVYFHCSALICDQLSSNFPLCSASCLVSSRSRRATGATEEEKMIVSLPGPILLLSDGSSFRDAVDSKGHGTSGYAAFKTMVAVVALAGVVATLSLISYLRKKRITVLNH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
83	N-linked (GlcNAc...) asparagine	12199704		UniProt
191	N-linked (GlcNAc...) asparagine	12199704		UniProt
457	O-linked (GalNAc...) threonine			UniProt
527	N-linked (GlcNAc...) asparagine	12199704		UniProt
unknown		12199704	G51640FO G90870DG G77537OB G91636VS G00176HZ G50757KG G03382KH G29483LI G32305RZ G10256JP G61207RZ G46687AB G75727PF G49874UX G80858MF G06110VR G55220VL	GlyConnect