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MIRAGE
Serine/threonine-protein kinase PINK1, mitochondrial
Summary
- UniProt ID
- Q9BXM7
- Gene Symbol
-
- PINK1
- Gene ID
- 65018
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q9BXM7
- The Human Metabolome Database
- HMDBP01217
- The O-GlcNAc Database
- Q9BXM7
- Re-Glyco
- Q9BXM7
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Autophagy
- Cytoplasm
- Disease variant
- Magnesium
- Metal-binding
- Mitochondrion inner membrane
- Mitochondrion outer membrane
- Neurodegeneration
- Parkinson disease
- Parkinsonism
- Phosphoprotein
- Primary mitochondrial disease
- Reference proteome
- Serine/threonine-protein kinase
- Transit peptide
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| chromatin |
| nucleus |
| cytoplasm |
| mitochondrion |
| mitochondrial inner membrane |
| cytoskeleton |
| membrane |
| axon |
| cell body |
| endoplasmic reticulum |
| GO Term |
|---|
| protein-containing complex binding |
| protein serine kinase activity |
| C3HC4-type RING finger domain binding |
| TORC2 complex binding |
Sequence
MAVRQALGRGLQLGRALLLRFTGKPGRAYGLGRPGPAAGCVRGERPGWAAGPGAEPRRVGLGLPNRLRFFRQSVAGLAARLQRQFVVRAWGCAGPCGRAVFLAFGLGLGLIEEKQAESRRAVSACQEIQAIFTQKSKPGPDPLDTRRLQGFRLEEYLIGQSIGKGCSAAVYEATMPTLPQNLEVTKSTGLLPGRGPGTSAPGEGQERAPGAPAFPLAIKMMWNISAGSSSEAILNTMSQELVPASRVALAGEYGAVTYRKSKRGPKQLAPHPNIIRVLRAFTSSVPLLPGALVDYPDVLPSRLHPEGLGHGRTLFLVMKNYPCTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPPDVRQLVRALLQREASKRPSARVAANVLHLSLWGEHILALKNLKLDKMVGWLLQQSAATLLANRLTEKCCVETKMKMLFLANLECETLCQAALLLCSWRAAL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 198 |
|
|||
| 199 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FOXO-mediated transcription of cell death genes | Homo sapiens |
| PINK1-PRKN Mediated Mitophagy | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060369 | Parkinson's disease 6 | |
| DOID:14330 | Parkinson's disease |
