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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Queuine tRNA-ribosyltransferase catalytic subunit 1
Summary
- UniProt ID
- Q9BXR0
- Gene Symbol
-
- QTRT1
- TGT
- TGUT
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9BXR0
- PubChem
- Q9BXR0
- The Human Metabolome Database
- HMDBP00844
- The O-GlcNAc Database
- Q9BXR0
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Glycosyltransferase
- Metal-binding
- Mitochondrion outer membrane
- Phosphoprotein
- Reference proteome
- Zinc
- tRNA processing
- Gene Ontology (GO)
| GO Term |
|---|
| tRNA modification |
| tRNA-guanine transglycosylation |
| GO Term |
|---|
| nucleus |
| protein-containing complex |
| transferase complex |
| cytosol |
| mitochondrial outer membrane |
| GO Term |
|---|
| metal ion binding |
| protein homodimerization activity |
| protein heterodimerization activity |
| tRNA-guanosine(34) queuine transglycosylase activity |
Sequence
MAGAATQASLESAPRIMRLVAECSRSRARAGELWLPHGTVATPVFMPVGTQATMKGITTEQLDALGCRICLGNTYHLGLRPGPELIQKANGLHGFMNWPHNLLTDSGGFQMVSLVSLSEVTEEGVRFRSPYDGNETLLSPEKSVQIQNALGSDIIMQLDDVVSSTVTGPRVEEAMYRSIRWLDRCIAAHQRPDKQNLFAIIQGGLDADLRATCLEEMTKRDVPGFAIGGLSGGESKSQFWRMVALSTSRLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSALVPTGNLQLRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHSDNTAALHHLTVHNIAYQLQLMSAVRTSIVEKRFPDFVRDFMGAMYGDPTLCPTWATDALASVGITLG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| tRNA modification in the nucleus and cytosol | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050759 | myotonic dystrophy type 2 | |
| DOID:0060285 | parietal foramina | |
| DOID:0090020 | split hand-foot malformation | |
| DOID:0090021 | split hand-foot malformation 1 | |
| DOID:0090022 | split hand-foot malformation 5 | |
| DOID:0090023 | split hand-foot malformation 4 | |
| DOID:0090025 | split hand-foot malformation 3 | |
| DOID:0090026 | split hand-foot malformation 6 | |
| DOID:0090027 | split hand-foot malformation 2 | |
| DOID:1324 | lung cancer |
