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Complement factor H-related protein 5
Summary
- UniProt ID
- Q9BXR6
- Gene Symbol
-
- CFHL5
- CFHR5
- FHR5
- Gene ID
- 81494
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hemolytic uremic syndrome
- Reference proteome
- Repeat
- Secreted
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| protein-containing complex |
| GO Term |
|---|
| complement activation, alternative pathway |
| cytolysis by host of symbiont cells |
| complement activation |
| negative regulation of protein binding |
| GO Term |
|---|
| complement component C3b binding |
| identical protein binding |
| protein heterodimerization activity |
Sequence
MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSLQNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCSDIFRYRHSVCINGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFRAICQEGKFEYPICE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 126 | N-linked (GlcNAc...) asparagine | |||
| 283 |
|
|||
| 400 | N-linked (GlcNAc...) asparagine |
G24954UD
G45395BF
G00912UN
G59626AS
G10486CT
G95865ZB
G43417UB
G29068FM
G43223CG
G49642SA
G31986NC
G10846ZT
G40574BA
G00273SJ
G08918WF
G48414YA
G41071NU
G86182NS
G49018RC
G72747WU
G70619PT
G06356OH
G08290VR
G84225JN
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of Complement cascade | Homo sapiens |
