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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Alpha-(1,6)-fucosyltransferase
Summary
- UniProt ID
- Q9BYC5
- Gene Symbol
-
- FUT8
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9BYC5
- PubChem
- Q9BYC5
- The Human Metabolome Database
- HMDBP05922
- RaftProt
- Q9BYC5
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Congenital disorder of glycosylation
- Disease variant
- Disulfide bond
- Glycosyltransferase
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- SH3 domain
- SH3-binding
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| Golgi apparatus |
| membrane |
| extracellular exosome |
| Golgi cisterna membrane |
| GO Term |
|---|
| SH3 domain binding |
| glycoprotein 6-alpha-L-fucosyltransferase activity |
| alpha-(1->6)-fucosyltransferase activity |
Sequence
MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYPTYPEAEK
Glycosylation Sites
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Maturation of spike protein | Homo sapiens |
| Reactions specific to the complex N-glycan synthesis pathway | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060249 | scoliosis | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:1059 | intellectual disability | |
| DOID:1068 | juvenile glaucoma | |
| DOID:10907 | microcephaly | |
| DOID:11211 | buphthalmos | |
| DOID:11212 | hydrophthalmos | |
| DOID:11832 | visual epilepsy |
