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Tubulin beta-4A chain
Summary
- UniProt ID
- Q9D6F9
- Gene Symbol
-
- Tubb4
- Tubb4a
- Gene ID
- 22153
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cilium biogenesis/degradation
- Cytoskeleton
- Direct protein sequencing
- GTP-binding
- Isopeptide bond
- Magnesium
- Metal-binding
- Microtubule
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| cell projection |
| neuronal cell body |
| myelin sheath |
| microtubule |
| axoneme |
| mitotic spindle |
| internode region of axon |
| intercellular bridge |
| cytoplasm |
| cilium |
| GO Term |
|---|
| cell projection organization |
| negative regulation of microtubule polymerization |
| microtubule-based process |
| GO Term |
|---|
| calcium ion binding |
| GTP binding |
| GTPase activity |
| structural constituent of cytoskeleton |
Sequence
MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGEFEEEAEEEVA
Glycosylation Sites
G49108TO
G76868JS
G13193DT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AURKA Activation by TPX2 | Mus musculus |
| Anchoring of the basal body to the plasma membrane | Mus musculus |
| Loss of Nlp from mitotic centrosomes | Mus musculus |
| Loss of proteins required for interphase microtubule organization from the centrosome | Mus musculus |
| Recruitment of NuMA to mitotic centrosomes | Mus musculus |
| Recruitment of mitotic centrosome proteins and complexes | Mus musculus |
| Regulation of PLK1 Activity at G2/M Transition | Mus musculus |
| Sealing of the nuclear envelope (NE) by ESCRT-III | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060798 | hypomyelinating leukodystrophy 6 |
