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Ubiquitin-like modifier-activating enzyme ATG7
Summary
- UniProt ID
- Q9D906
- Gene Symbol
-
- Apg7l
- Atg7
- Gene ID
- 74244
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Autophagy
- Biological rhythms
- Cytoplasm
- Isopeptide bond
- Phosphoprotein
- Protein transport
- Reference proteome
- Ubl conjugation
- Ubl conjugation pathway
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| membrane |
| presynapse |
| cytosol |
| perinuclear region of cytoplasm |
| phagophore assembly site |
| axoneme |
| dopaminergic synapse |
| GO Term |
|---|
| Atg12 activating enzyme activity |
| Atg8 activating enzyme activity |
Sequence
MGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV
Glycosylation Sites
G70101JE
G64527OM
G41954QW
G76393RH
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen processing: Ubiquitination & Proteasome degradation | Mus musculus |
| Macroautophagy | Mus musculus |
| Neutrophil degranulation | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050908 | myelodysplastic syndrome | |
| DOID:14330 | Parkinson's disease | |
| DOID:9074 | systemic lupus erythematosus |
