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Casein kinase I isoform delta

Summary

UniProt ID: Q9DC28
Gene Symbol: Csnk1d Hckid
Gene ID: 104318
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q9DC28
PubChem: Q9DC28
The O-GlcNAc Database: Q9DC28
RaftProt: Q9DC28
O-GlcNAcAtlas: Q9DC28
Re-Glyco: Q9DC28

Annotation

Keyword: 3D-structure ATP-binding Alternative splicing Biological rhythms Cell membrane Cytoskeleton Golgi apparatus Methylation Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Wnt signaling pathway

Gene Ontology (GO)

Displaying entries **1 - 5** of 30 in total

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GO Term	Evidence Code	Reference
protein phosphorylation	ISS	GO_REF
protein phosphorylation	ISO	GO_REF GO_REF
protein phosphorylation	IDA	PMID
protein phosphorylation	IMP	PMID
endocytosis	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

microtubule nucleation

spindle organization [inference]

spindle assembly

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

vesicle-mediated transport [inference]

endocytosis

cell cycle process [inference]

spindle organization [inference]

spindle assembly

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

midbrain dopaminergic neuron differentiation

dopaminergic neuron differentiation [inference]

midbrain dopaminergic neuron differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

microtubule nucleation

spindle organization [inference]

spindle assembly

Golgi organization

cilium organization [inference]

cilium assembly [inference]

non-motile cilium assembly

organelle assembly [inference]

cilium assembly [inference]

non-motile cilium assembly

membraneless organelle assembly [inference]

spindle assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

non-motile cilium assembly

organelle assembly [inference]

cilium assembly [inference]

non-motile cilium assembly

membraneless organelle assembly [inference]

spindle assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

non-motile cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly [inference]

non-motile cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

non-motile cilium assembly

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

midbrain dopaminergic neuron differentiation

dopaminergic neuron differentiation [inference]

midbrain dopaminergic neuron differentiation

rhythmic process [inference]

circadian rhythm [inference]

circadian regulation of gene expression

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to Golgi apparatus

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to microtubule organizing center [inference]

protein localization to centrosome

protein localization to cilium

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

import into cell [inference]

endocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of non-canonical Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of circadian rhythm

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of non-canonical Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of non-canonical Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

circadian regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

circadian regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	Reference
nucleus	EXP	PMID PMID
nucleus	IDA	PMID
nucleus	IEA	GO_REF
nucleoplasm	ISO	GO_REF
nucleoplasm	TAS	Reactome Reactome Reactome Reactome

GO Hierarchy

cellular component

cellular anatomical structure [inference]

microtubule organizing center [inference]

centrosome

cytosol

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

intracellular membrane-bounded organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

spindle

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular membraneless organelle [inference]

spindle

cytoskeleton [inference]

actin cytoskeleton

perinuclear region of cytoplasm

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule [inference]

spindle microtubule

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
protein kinase activity	ISS	GO_REF
protein kinase activity	ISO	GO_REF
protein kinase activity	IDA	PMID PMID
protein kinase activity	IMP	PMID
protein kinase activity	IGI	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity

protein kinase activity

protein serine/threonine kinase activity

tau-protein kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity

tau-protein kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity

tau-protein kinase activity

protein serine kinase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	PubMed ID	GlyTouCan ID	Source
344	22645316 35822049 36852467 40885482	G49108TO	The O-GlcNAc Database
380		G03238UC	GlyGen
382	22645316 35822049 36852467 40885482	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
AURKA Activation by TPX2	Mus musculus
Anchoring of the basal body to the plasma membrane	Mus musculus
COPII-mediated vesicle transport	Mus musculus
Loss of Nlp from mitotic centrosomes	Mus musculus
Loss of proteins required for interphase microtubule organization from the centrosome	Mus musculus
Major pathway of rRNA processing in the nucleolus and cytosol	Mus musculus
Recruitment of NuMA to mitotic centrosomes	Mus musculus
Recruitment of mitotic centrosome proteins and complexes	Mus musculus
Regulation of PLK1 Activity at G2/M Transition	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1094	attention deficit hyperactivity disorder	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements