GlyCosmos Portal

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Toll-like receptor 6

Summary

UniProt ID

Q9EPW9

Gene Symbol

Tlr6

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9EPW9
PubChem: Q9EPW9

Annotation

Keyword

3D-structure
Cell membrane
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Golgi apparatus
Inflammatory response
Innate immunity
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 24 in total

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GO Term
positive regulation of canonical NF-kappaB signal transduction
toll-like receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
response to bacterial lipoprotein
positive regulation of interleukin-12 production
TRIF-dependent toll-like receptor signaling pathway
detection of diacyl bacterial lipopeptide
cellular response to diacyl bacterial lipopeptide
cellular response to oxidised low-density lipoprotein particle stimulus
positive regulation of NLRP3 inflammasome complex assembly

Displaying **all 4** entries
GO Term
Golgi apparatus
phagocytic vesicle membrane
membrane raft
Toll-like receptor 2-Toll-like receptor 6 protein complex

Displaying **all 7** entries
GO Term
transmembrane signaling receptor activity
signaling receptor activity
NAD+ nucleotidase, cyclic ADP-ribose generating
identical protein binding
Toll-like receptor 2 binding
diacyl lipopeptide binding
lipopeptide binding

Annotation information from UniProt.

Sequence

MSQDRKPIVGSFHFVCALALIVGSMTPFSNELESMVDYSNRNLTHVPKDLPPRTKALSLSQNSISELRMPDISFLSELRVLRLSHNRIRSLDFHVFLFNQDLEYLDVSHNRLQNISCCPMASLRHLDLSFNDFDVLPVCKEFGNLTKLTFLGLSAAKFRQLDLLPVAHLHLSCILLDLVSYHIKGGETESLQIPNTTVLHLVFHPNSLFSVQVNMSVNALGHLQLSNIKLNDENCQRLMTFLSELTRGPTLLNVTLQHIETTWKCSVKLFQFFWPRPVEYLNIYNLTITERIDREEFTYSETALKSLMIEHVKNQVFLFSKEALYSVFAEMNIKMLSISDTPFIHMVCPPSPSSFTFLNFTQNVFTDSVFQGCSTLKRLQTLILQRNGLKNFFKVALMTKNMSSLETLDVSLNSLNSHAYDRTCAWAESILVLNLSSNMLTGSVFRCLPPKVKVLDLHNNRIMSIPKDVTHLQALQELNVASNSLTDLPGCGAFSSLSVLVIDHNSVSHPSEDFFQSCQNIRSLTAGNNPFQCTCELRDFVKNIGWVAREVVEGWPDSYRCDYPESSKGTALRDFHMSPLSCDTVLLTVTIGATMLVLAVTGAFLCLYFDLPWYVRMLCQWTQTRHRARHIPLEELQRNLQFHAFVSYSEHDSAWVKNELLPNLEKDDIRVCLHERNFVPGKSIVENIINFIEKSYKAIFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLEPILQNNIPSRYHKLRALMAQRTYLEWPTEKGKRGLFWANLRASFIMKLALVNEDDVKT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
42	N-linked (GlcNAc...) asparagine			UniProt GlyGen
114	N-linked (GlcNAc...) asparagine		G43769ZW	UniProt GlyGen
144	N-linked (GlcNAc...) asparagine	19931471		UniProt GlyGen
195	N-linked (GlcNAc...) asparagine	19931471		UniProt GlyGen
214	N-linked (GlcNAc...) asparagine	19931471		UniProt GlyGen
253	N-linked (GlcNAc...) asparagine	19931471	G80920RR	UniProt GlyGen
285				UniProt GlyGen
359	N-linked (GlcNAc...) asparagine	19931471		UniProt GlyGen
401	N-linked (GlcNAc...) asparagine	19931471		UniProt GlyGen
434	N-linked (GlcNAc...) asparagine	19931471		UniProt GlyGen