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Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

Summary

UniProt ID

Q9HAN9

Gene Symbol

NMNAT1
NMNAT

Organism

Homo sapiens (human)

External Links

GlyGen: Q9HAN9
PubChem: Q9HAN9
The Human Metabolome Database: HMDBP00335
The O-GlcNAc Database: Q9HAN9

Annotation

Keyword

3D-structure
ATP-binding
Deafness
Direct protein sequencing
Disease variant
Dwarfism
Intellectual disability
Leber congenital amaurosis
Magnesium
NAD
Nucleotidyltransferase
Nucleus
Phosphoprotein
Pyridine nucleotide biosynthesis
Reference proteome
Zinc

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
NAD biosynthetic process
positive regulation of MAPK cascade
negative regulation of apoptotic DNA fragmentation
response to wounding
negative regulation of neuron apoptotic process
ATP generation from poly-ADP-D-ribose
nucleotide biosynthetic process
negative regulation of DNA-templated transcription

Displaying **all 4** entries
GO Term
nucleoplasm
nuclear body
chromatin
nucleus

Displaying **all 5** entries
GO Term
identical protein binding
nicotinamide-nucleotide adenylyltransferase activity
nicotinate-nucleotide adenylyltransferase activity
ATP binding
protein ADP-ribosyltransferase-substrate adaptor activity

Annotation information from UniProt.

Sequence

MENSEKTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGLIPAYHRVIMAELATKNSKWVEVDTWESLQKEWKETLKVLRHHQEKLEASDCDHQQNSPTLERPGRKRKWTETQDSSQKKSLEPKTKAVPKVKLLCGADLLESFAVPNLWKSEDITQIVANYGLICVTRAGNDAQKFIYESDVLWKHRSNIHVVNEWIANDISSTKIRRALRRGQSIRYLVPDLVQEYIEKHNLYSSESEDRNAGVILAPLQRNTAEAKT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites