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MIRAGE
Disintegrin and metalloproteinase domain-containing protein 21

Summary
UniProt ID
Q9JI76
Gene Symbol
  • Adam21
  • Adam31
Gene ID
56622
Organism
Mus musculus (house mouse)
PubChem
Q9JI76
Re-Glyco
Q9JI76
Annotation
Keyword
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Zinc
  • Zymogen
Gene Ontology (GO)
Displaying all 4 entries
GO Term
membrane
axon
neuron projection
neuronal cell body
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
proteolysis
Displaying all 2 entries
GO Term
metal ion binding
metalloendopeptidase activity
Annotation information from UniProt.
Sequence
MECFIMLGADARTLMRVTLLLLWLKALPSLIDLSQTGSTQYLSSPEVVIPLKVTSRARGAKNSEWLSYSLVFGGRRHVVHMRVKKLLVSTHIPVLTYTEEHTPLSDYPFVPSDCYYHGYVEGALESLVAFSACNGGLQGVLQMNGFSYEIEPIKHSSTFEHLVYTLNNNKTQFPPMLCSLTEKRLLYQPFGVEEAKKSAMKQNYGKLWPHMWFLELAVVVDYGFFTNAQQNLSKVRGDVVLVVNMVDSMYKPLDTYVTLVGIEIWNRGNVLPMENIHQVLEDFSHWKQISLSQVHHDAAHIFIRSSLISVLGIAYIAGICRPPLDCGVENFQGDAWSLFANTVAHELGHTFGMKHDEESCSCGKSGCVMSTFRVPAERFTNCSYSDFMKTTLNQGTCLYNHPRPGAGFLVKRCGNGMVESEEECDCGSVQECEQDPCCFLNCTLRPAAACSFGLCCKDCKFMLLGELCRPKINECDLPEWCNGTSHQCPEDGYVQDGVPCGAGAYCYQKQCNNHDQQCREIFGKGARSASHNCYKEINLQGNRFGHCGTDGTVFLKCRMSDVFCGKVHCENVEDIHHPQAPYVLQNIYANGITCWSTGHCLGMGVPDVGEVKDGTTCGVGKICLHKKCVSLSVLSNACLPETCNRKGVCNNKHHCHCDYGWSPPFCLHRGYGGSIDSGPTSQKRRVIITVLSITVPVLSILICLLIAGLYRIYCKIPSGPKETKASSPG
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
169 N-linked (GlcNAc...) asparagine
231 N-linked (GlcNAc...) asparagine
381 N-linked (GlcNAc...) asparagine
441 N-linked (GlcNAc...) asparagine
482 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Interaction With Cumulus Cells And The Zona Pellucida Mus musculus
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025