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Alpha-actinin-2

Summary

UniProt ID

Q9JI91

Gene Symbol

Actn2

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9JI91
PubChem: Q9JI91
RaftProt: Q9JI91

Annotation

Keyword

Actin-binding
Calcium
Cytoplasm
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
actin cytoskeleton organization
sarcomere organization
muscle cell development
phospholipase C-activating angiotensin-activated signaling pathway
negative regulation of protein localization to cell surface
positive regulation of endocytic recycling
positive regulation of cation channel activity
muscle contraction
regulation of membrane potential
positive regulation of potassium ion transport

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GO Term
cell junction
Z disc
plasma membrane
sarcomere
cell projection
postsynaptic actin cytoskeleton
striated muscle thin filament
focal adhesion
filopodium
cortical actin cytoskeleton

Displaying entries **1 - 10** of 12 in total

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GO Term
phosphatidylinositol-4,5-bisphosphate binding
cytoskeletal protein binding
nuclear receptor coactivator activity
protein-macromolecule adaptor activity
identical protein binding
transmembrane transporter binding
actin filament binding
FATZ binding
LIM domain binding
titin binding

Annotation information from UniProt.

Sequence

MNQIEPGVQYNYVYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSILAIQNEVEKVIQSYSIRISSSNPYSTVTMDELRNKWDKVKQLVPVRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPPYSGPGSVPGALDYTAFSSALYGESDL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
714			G31852PQ	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Platelet degranulation	Mus musculus
RAF/MAP kinase cascade	Mus musculus
Striated Muscle Contraction	Mus musculus
Unblocking of NMDA receptors, glutamate binding and activation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements