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B-cell receptor CD22

Summary

UniProt ID

Q9N1E5

Gene Symbol

CD22
SIGLEC2

Organism

Pan paniscus (pygmy chimpanzee)

External Links

The Human Metabolome Database: HMDBP14335
Re-Glyco: Q9N1E5

Annotation

Keyword

Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Isopeptide bond
Lectin
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
early endosome
external side of plasma membrane
neuronal cell body membrane
recycling endosome
extracellular exosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 7** entries
GO Term
negative regulation of immunoglobulin production
cell adhesion
regulation of endocytosis
regulation of B cell proliferation
B cell activation
negative regulation of calcium-mediated signaling
negative regulation of B cell receptor signaling pathway

Displaying **all 4** entries
GO Term
protein phosphatase binding
sialic acid binding
CD4 receptor binding
carbohydrate binding

Annotation information from UniProt.

Sequence

MHLLGPWLLLLVLEYLAFSDSSKWAFEHPETLYAWEGACVWIPCTYRALDRDLESFILFHNPEYNKNTSKFDGTRLYESTKDGKVPSEQKRVQFLGDKNKNCTLSIHPVHVNDSGQLGLRMESKTAKWMERIHLNVSERPFPPHIQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEGVPMRQAAVTSTSLTIKSVFTRSELKFSPQWSHHGKIVTCQLQDADGKFLSNDTVQLNVKHTPKLEIKVTPSDAIVREGESVTMTCEVSSSNPEYTTISWLKDGTSLKKQNTLMLNLHEVTKDQSGKYCCQVSNDVGPGRSAEVFLQVQYAPEPSTVQILHSPAVEGSQVEFLCMSLANPLPTNYTWYHNGKEMQGRTEEKVHIPKILPWHAGTYSCVAENILGTGQRGPGAELDVQYPPKKVTTVIQNPTPIREGDTVTLSCNYNSSNPSVTRYEWKPHGAWEEPSLGVLKIQNVGWGNTTIACAACNSWCSWASPVALNVQYAPRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQFFWEKNGRLLGKESRLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPYHSQKLRLEPVKVQHSGAYWCQGTNSVGKGHSPLSTLTVYYSPETIGRRVAVGFGSCLAILILAICGLKLQRRWKRTQSQQGLQENSSGQSFFVRNKKVRRAPLSEGPHSLGCYNPMMEDGISYTTLRFPETNIPRTGDAETSEMQSPPPDCDDTVTYSVLHKRQMGDYENVIPDFSEDEGIHYSELIQFGVGERPQAQENVDYVILKH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 13 in total

1

2

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Position	Description	Source
67	N-linked (GlcNAc...) asparagine	UniProt
101	N-linked (GlcNAc...) asparagine	UniProt
112	N-linked (GlcNAc...) asparagine	UniProt
135	N-linked (GlcNAc...) asparagine	UniProt
164	N-linked (GlcNAc...) asparagine	UniProt
231	N-linked (GlcNAc...) asparagine	UniProt
363	N-linked (GlcNAc...) asparagine	UniProt
428	N-linked (GlcNAc...) asparagine	UniProt
445	N-linked (GlcNAc...) asparagine	UniProt
448	N-linked (GlcNAc...) asparagine	UniProt