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Carbohydrate-responsive element-binding protein

Summary

UniProt ID

Q9NP71

Gene Symbol

BHLHD14
MIO
MLXIPL
WBSCR14

Gene ID

51085

Organism

Homo sapiens (human)

External Links

GlyGen: Q9NP71
PubChem: Q9NP71
The O-GlcNAc Database: Q9NP71
O-GlcNAcAtlas: Q9NP71
Re-Glyco: Q9NP71

Annotation

Keyword

3D-structure
Alternative splicing
DNA-binding
Nucleus
Phosphoprotein
Reference proteome
Repressor
Transcription regulation
Williams-Beuren syndrome

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
nucleoplasm
cytosol
transcription regulator complex
chromatin
nucleus
cytoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 19 in total

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GO Term
positive regulation of glycolytic process
positive regulation of lipid biosynthetic process
regulation of DNA-templated transcription
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
positive regulation of transcription from RNA polymerase II promoter by glucose
glucose mediated signaling pathway
negative regulation of peptidyl-serine phosphorylation
positive regulation of fatty acid biosynthetic process
negative regulation of oxidative phosphorylation

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GO Term
DNA-binding transcription activator activity
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
DNA-binding transcription factor activity
protein heterodimerization activity
RNA polymerase II-specific DNA-binding transcription factor binding
DNA-binding transcription factor binding
DNA-binding transcription repressor activity, RNA polymerase II-specific

Annotation information from UniProt.

Sequence

MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSDSLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

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Position	GlyTouCan ID	Source
258	G49108TO	The O-GlcNAc Database
260	G49108TO	The O-GlcNAc Database
262	G49108TO	The O-GlcNAc Database
265	G49108TO	The O-GlcNAc Database
287	G49108TO	The O-GlcNAc Database
458		GlyGen
468		GlyGen
519	G49108TO	GlyGen
572		GlyGen
576		GlyGen

Feature

Domains & sites

PTM

ProtVista

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
AMPK inhibits chREBP transcriptional activation activity	Homo sapiens
ChREBP activates metabolic gene expression	Homo sapiens
PKA-mediated phosphorylation of key metabolic factors	Homo sapiens
PP2A-mediated dephosphorylation of key metabolic factors	Homo sapiens

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:3393	coronary artery disease	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements