Lactosylceramide 4-alpha-galactosyltransferase

Summary
UniProt ID
Q9NPC4
Gene Symbol
  • A4GALT
  • A14GALT
  • A4GALT1
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0015835
GlyGen
Q9NPC4
PubChem
Q9NPC4
SwissLipids
The Human Metabolome Database
HMDBP00874
Annotation
Keyword
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Lipid biosynthesis
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Gene Ontology (GO)
Sequence
MSKPPDLLLRLLRGAPRQRVCTLFIIGFKFTFFVSIMIYWHVVGEPKEKGQLYNLPAEIPCPTLTPPTPPSHGPTPGNIFFLETSDRTNPNFLFMCSVESAARTHPESHVLVLMKGLPGGNASLPRHLGISLLSCFPNVQMLPLDLRELFRDTPLADWYAAVQGRWEPYLLPVLSDASRIALMWKFGGIYLDTDFIVLKNLRNLTNVLGTQSRYVLNGAFLAFERRHEFMALCMRDFVDHYNGWIWGHQGPQLLTRVFKKWCSIRSLAESRACRGVTTLPPEAFYPIPWQDWKKYFEDINPEELPRLLSATYAVHVWNKKSQGTRFEATSRALLAQLHARYCPTTHEAMKMYL
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
65
68
121 N-linked (GlcNAc...) asparagine
203 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Glycosphingolipid biosynthesis Homo sapiens
Disease
Displaying entries 1 - 10 of 17 in total
DO ID Disease Name Source
DOID:1074 kidney failure
DOID:1240 leukemia
DOID:12554 hemolytic-uremic syndrome
DOID:162 cancer
DOID:2452 thrombophilia
DOID:2531 hematologic cancer
DOID:299 adenocarcinoma
DOID:3305 teratocarcinoma
DOID:3717 gastric adenocarcinoma
DOID:4257 Caffey disease

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024