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Dual oxidase 1

Summary

UniProt ID

Q9NRD9

Gene Symbol

DUOX1
DUOX
LNOX1
THOX1

Organism

Homo sapiens (human)

External Links

GlyGen: Q9NRD9
PubChem: Q9NRD9
The Human Metabolome Database: HMDBP07070
The O-GlcNAc Database: Q9NRD9

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Cell membrane
FAD
Glycoprotein
Hydrogen peroxide
Metal-binding
NADP
Reference proteome
Repeat
Signal
Thyroid hormones biosynthesis
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

1

2

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GO Term
response to cAMP
cuticle development
hydrogen peroxide biosynthetic process
hydrogen peroxide catabolic process
thyroid hormone generation
defense response
response to oxidative stress
cytokine-mediated signaling pathway
hormone biosynthetic process
superoxide anion generation

Displaying **all 6** entries
GO Term
plasma membrane
cell leading edge
apical plasma membrane
NADPH oxidase complex
endoplasmic reticulum
cell surface

Displaying **all 8** entries
GO Term
peroxidase activity
superoxide-generating NAD(P)H oxidase activity
NADH oxidase H202-forming activity
NADPH oxidase H202-forming activity
calcium ion binding
NADP binding
NAD(P)H oxidase H2O2-forming activity
heme binding

Annotation information from UniProt.

Sequence

MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDVLVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIGTLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVLVYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEEERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	GlyTouCan ID	Source
94	N-linked (GlcNAc...) asparagine		UniProt GlyGen
342	N-linked (GlcNAc...) asparagine		UniProt GlyGen
354	N-linked (GlcNAc...) asparagine		UniProt GlyGen
461	N-linked (GlcNAc...) asparagine		UniProt GlyGen
534	N-linked (GlcNAc...) asparagine		UniProt GlyGen
1302		G49108TO	GlyGen The O-GlcNAc Database