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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Summary
- UniProt ID
- Q9NSC7
- Gene Symbol
-
- ST6GALNAC1
- SIAT7A
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9NSC7
- The Human Metabolome Database
- HMDBP11953
- The O-GlcNAc Database
- Q9NSC7
Annotation
- Keyword
-
- Disease variant
- Disulfide bond
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| host-mediated regulation of intestinal microbiota composition |
| protein glycosylation |
| oligosaccharide biosynthetic process |
| GO Term |
|---|
| Golgi membrane |
| GO Term |
|---|
| sialyltransferase activity |
| alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity |
Sequence
MRSCLWRCRHLSQGVQWSLLLAVLVFFLFALPSFIKEPQTKPSRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGNGGQTRKLTASRTVSEKHQGKAATTAKTLIPKSQHRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPFQSPTTQRNQRLKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPNLTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTAKAKN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 171 |
|
|||
| 175 |
|
|||
| 177 |
|
|||
| 300 | N-linked (GlcNAc...) asparagine |
|
||
| 311 | N-linked (GlcNAc...) asparagine |
|
||
| 331 | N-linked (GlcNAc...) asparagine |
|
||
| 364 |
|
|||
| 375 | N-linked (GlcNAc...) asparagine |
|
||
| 460 | N-linked (GlcNAc...) asparagine |
|
||
| 587 |
|
G49108TO
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Sialic acid metabolism | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:235 | colonic benign neoplasm | |
| DOID:2394 | ovarian cancer | |
| DOID:2871 | endometrial carcinoma | |
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:4001 | ovarian carcinoma | |
| DOID:4007 | bladder carcinoma | |
| DOID:4766 | embryoma | |
| DOID:5419 | schizophrenia | |
| DOID:5517 | stomach carcinoma | |
| DOID:5672 | large intestine cancer |
