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Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4

Summary

UniProt ID

Q9QXZ0

Gene Symbol

Macf1
Acf7
Aclp7
Kiaa0754
Macf

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9QXZ0
The O-GlcNAc Database: Q9QXZ0
RaftProt: Q9QXZ0
O-GlcNAcAtlas: Q9QXZ0

Annotation

Keyword

Acetylation
Actin-binding
Alternative splicing
Calcium
Cell membrane
Cell projection
Cytoskeleton
Direct protein sequencing
Golgi apparatus
Leucine-rich repeat
Metal-binding
Microtubule
Phosphoprotein
Reference proteome
Repeat
SH3 domain
Wnt signaling pathway

Gene Ontology (GO)

Displaying entries **11 - 16** of 16 in total

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1

2
GO Term
intermediate filament cytoskeleton organization
intermediate filament bundle assembly
regulation of focal adhesion assembly
positive regulation of Wnt signaling pathway
Wnt signaling pathway
post-translational protein targeting to endoplasmic reticulum membrane

Displaying **all 10** entries
GO Term
keratin filament
cytoplasm
Golgi apparatus
microtubule
cell cortex
actin cytoskeleton
microtubule cytoskeleton
membrane
postsynaptic density
ruffle membrane

Displaying **all 8** entries
GO Term
calcium ion binding
microtubule binding
actin binding
keratin filament binding
microtubule minus-end binding
ATP hydrolysis activity
structural molecule activity
actin filament binding

Annotation information from UniProt.

Sequence

MGKPLSRPDCLRRNPTCLGKGEDEDGYIEDCYVPQRSIYDTMRINEQIDQGSKLNQTSKSTMEKMEGSTISSNGTLGASSNVFEARGPEGKKLDERIIFDALKLSSDVQKSAPVPPRRRPNAERKDNVNRRSWKSFMPPNFPEFAERMEASLSEVSEAGASNPSLQEKKESSSALTESSGHFDHREPQSESVTLEHMSKSVDIPEVQNVKNLRDCQDFKFQQHSESSPHEFQPLGSEAAAASGNTDEMQEHRFSSATWPRAMKSSSKGGFSEKQYPLGDTACAVELPPLSPCLSEELLDPELHMLITPSLREKTESELKFEEDERWIMMEAEEEWEEEKLSEERKSLVTNEETSLADPLEESDQANSVPAVEDGSDRVAVSGTSDHLALHQMCCSVDLQPTRDQLASVPRGSPPDCTCVPAGDTVISEVKNRPDQGLEGLTSGLQCPVEAEQLSDTDSVQMFLELEKECLCEEGVTSSAELLSQASSEGLAPTQDAEDSLLISHFPGAALEQEQHVGFLSVRIKDPDTGLDGEYCNALDSSQVPKAVELCAQPDSGRDASTISKECEKVPFSPKIGGEFKLLADLEPHSELDTGGLLNSNLRASCEENLPVFIASELAKENGNLSQVDCSQTEGNVEEYMERIPLSFAFNYEQDVTSGPEVEVFSSDSNLLTDEIHLESGKGALISQEDSNLASLGNVDLCELSMEKVCDKDGETKEPGCQGKLLGNGAPAQFPTDFQRRSSESEVLSLHLLAGELRLNKAGAETMSDREPQLSMALSQEGELEMRDLDSTLNIFPEEQISKASNTVPGLEEWISSQQRPVPAAVVPMVENALDAVTPMPGEDIPAVALTASEGPAANASASDGTAAATPIVPIPEEDIPGASVVILVEDVMTAAISAPEQAAASSGAVPPVETVTVPIIDEDVTSEEPDTQAAEMFLPEEPAIPTPAGPTAEEPDTPTVPVSTAEEPSMPPPAGPTPEESAAPTLKEPTPEKPDTQVVSSSIPEWSATPATAVPAKEIFSPDGPFLEGTTHTDSVPISEETPVLENASSPGMGIKECLDSSAFGIKEVPGTMIHGKVPLAATDGLNSHELFQKDQVDPLQVKLQQVNGLGQGLIQSAGKNCDVQGLEHDMDEINTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLERRWTDLLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTAKIHQQIIRHKALEEEIENHATDVHQAVKIGQSLSSLTCPAEQGIMSEKLDSLQARYSEIQDRCCRKASLLEQALFNARLFGEDEVEVLNWLAEVEDKLSTVFVKDYRQDVLQKQHADHLALNEEIINRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITLTSSKALRTLEQARQLATKFHSTYEELTGWLREAEEELAASGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSHALLELVPWRAREGLDKLVSDANEQYKLISDTVGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRGEIFSTCGEEQKAVLQEKTECLIQQYEAVSLLNSERYARLERAQVLVNQFWETYEELSPWAEETLALIAQLPPPAVDHEQLRQQQEEMRQLRESIAEHKPHIDKILKIGPQLKELNPEEGKMVEEKYQKAENMYAQIKDEVRQRALALDEAVSQSAQFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARSEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVKKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVATVNKAGSELLESSAGDDASSLRSRLETMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELNRMENQLSASKPTGGLPETAREQLDTHMELHSQLRAKEEIYNQLLDKGRLMLLSRGDSGSGSKTEQSVALLEQKWHAVSSKVEERKLEEALSLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNDHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLAGDTQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIEGSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEEFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNTAVAMGEAILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALITEHQSFMEEMTRKQPDVDRVTKTYKRKSVEPTHAPFMEKSRSGSRKSLNQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVISSSGSKLKRPTPAFHSSRTSLAGDTSNSSSPASTGAKANRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGSSRRGLTKPSKIPTMSKKTTTASPRTPGPKR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites