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Interleukin-12 subunit alpha

Summary

UniProt ID

Q9R103

Gene Symbol

Il12a

Gene ID

84405

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q9R103
Re-Glyco: Q9R103

Annotation

Keyword

Cytokine
Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
extracellular space
cytoplasm
cell surface
interleukin-12 complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 32 in total

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GO Term
response to lipopolysaccharide
negative regulation of interleukin-17 production
defense response to protozoan
cellular response to lipopolysaccharide
extrinsic apoptotic signaling pathway
negative regulation of vascular endothelial growth factor signaling pathway
response to UV-B
negative regulation of smooth muscle cell proliferation
positive regulation of natural killer cell activation
positive regulation of smooth muscle cell apoptotic process

Displaying **all 6** entries
GO Term
cytokine activity
growth factor activity
protein heterodimerization activity
interleukin-12 receptor binding
interleukin-12 beta subunit binding
interleukin-27 binding

Annotation information from UniProt.

Sequence

MCQSRYLLFLATLVLLNHLTSARVIPVSGPAKCLNQSQNLLKTTDDMVRTAREKLKHYSCTAGDIDHEDITRDKTSTLEACLPLELHKNESCLATKETSSIIRGSCLPPQKTSLMMTLCLGSIYEDLKMYQSEFQAINAALQSHNHQQITLDRNMLMAIDELMRSLNHSGETLHQKAPMGEADPYRVKMKLCILLHAFSTRVMTINRVMNYLSSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites