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Forkhead box protein O1

Summary

UniProt ID

Q9R1E0

Gene Symbol

Foxo1
Fkhr
Foxo1a

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9R1E0
PubChem: Q9R1E0
The O-GlcNAc Database: Q9R1E0
O-GlcNAcAtlas: Q9R1E0

Annotation

Keyword

Acetylation
Activator
Apoptosis
Autophagy
Cytoplasm
DNA-binding
Differentiation
Methylation
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 41 in total

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GO Term
canonical Wnt signaling pathway
regulation of DNA-templated transcription
regulation of transcription by RNA polymerase II
DNA damage response
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
regulation of transcription initiation by RNA polymerase II
cellular response to starvation
blood vessel development
regulation of gluconeogenesis

Displaying **all 3** entries
GO Term
nucleoplasm
nucleus
cytoplasm

Displaying entries **1 - 10** of 14 in total

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GO Term
DNA binding
transcription factor binding
protein phosphatase 2A binding
promoter-specific chromatin binding
chromatin DNA binding
ubiquitin protein ligase binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription repressor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity

Annotation information from UniProt.

Sequence

MAEAPQVVETDPDFEPLPRQRSCTWPLPRPEFNQSNSTTSSPAPSGGAAANPDAAASLASASAVSTDFMSNLSLLEESEDFARAPGCVAVAAAAAASRGLCGDFQGPEAGCVHPAPPQPPPTGPLSQPPPVPPSAAAAAGPLAGQPRKTSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKASLQSGQEGPGDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGDGDVHSLVYPPSAAKMASTLPSLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGSMMQQTPCYSFAPPNTSLNSPSPNYSKYTYGQSSMSPLPQMPMQTLQDSKSSYGGLNQYNCAPGLLKELLTSDSPPHNDIMSPVDPGVAQPNSRVLGQNVMMGPNSVMPAYGSQASHNKMMNPSSHTHPGHAQQTASVNGRTLPHVVNTMPHTSAMNRLTPVKTPLQVPLSHPMQMSALGSYSSVSSCNGYGRMGVLHQEKLPSDLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	GlyTouCan ID	Source
644	G49108TO	GlyGen
645	G49108TO	GlyGen
646	G49108TO	GlyGen The O-GlcNAc Database
651	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
AKT phosphorylates targets in the nucleus	Mus musculus
AKT-mediated inactivation of FOXO1A	Mus musculus
FOXO-mediated transcription of cell cycle genes	Mus musculus
MAPK6/MAPK4 signaling	Mus musculus
Regulation of FOXO transcriptional activity by acetylation	Mus musculus
Regulation of localization of FOXO transcription factors	Mus musculus