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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Intercellular adhesion molecule 5
Summary
- UniProt ID
- Q9UMF0
- Gene Symbol
-
- ICAM5
- TLCN
- TLN
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell adhesion
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cell-cell adhesion |
| regulation of synapse assembly |
| phagocytosis |
| cell adhesion |
| GO Term |
|---|
| plasma membrane |
| glutamatergic synapse |
| GO Term |
|---|
| integrin binding |
Sequence
MPGPSPGLRRALLGLWAALGLGLFGLSAVSQEPFWADLQPRVAFVERGGSLWLNCSTNCPRPERGGLETSLRRNGTQRGLRWLARQLVDIREPETQPVCFFRCARRTLQARGLIRTFQRPDRVELMPLPPWQPVGENFTLSCRVPGAGPRASLTLTLLRGAQELIRRSFAGEPPRARGAVLTATVLARREDHGANFSCRAELDLRPHGLGLFENSSAPRELRTFSLSPDAPRLAAPRLLEVGSERPVSCTLDGLFPASEARVYLALGDQNLSPDVTLEGDAFVATATATASAEQEGARQLVCNVTLGGENRETRENVTIYSFPAPLLTLSEPSVSEGQMVTVTCAAGAQALVTLEGVPAAVPGQPAQLQLNATENDDRRSFFCDATLDVDGETLIKNRSAELRVLYAPRLDDSDCPRSWTWPEGPEQTLRCEARGNPEPSVHCARSDGGAVLALGLLGPVTRALSGTYRCKAANDQGEAVKDVTLTVEYAPALDSVGCPERITWLEGTEASLSCVAHGVPPPDVICVRSGELGAVIEGLLRVAREHAGTYRCEATNPRGSAAKNVAVTVEYGPRFEEPSCPSNWTWVEGSGRLFSCEVDGKPQPSVKCVGSGGATEGVLLPLAPPDPSPRAPRIPRVLAPGIYVCNATNRHGSVAKTVVVSAESPPEMDESTCPSHQTWLEGAEASALACAARGRPSPGVRCSREGIPWPEQQRVSREDAGTYHCVATNAHGTDSRTVTVGVEYRPVVAELAASPPGGVRPGGNFTLTCRAEAWPPAQISWRAPPGALNIGLSSNNSTLSVAGAMGSHGGEYECAATNAHGRHARRITVRVAGPWLWVAVGGAAGGAALLAAGAGLAFYVQSTACKKGEYNVQEAESSGEAVCLNGAGGGAGGAAGAEGGPEAAGGAAESPAEGEVFAIQLTSA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 54 | N-linked (GlcNAc...) (high mannose) asparagine | |||
| 74 | N-linked (GlcNAc...) asparagine |
|
||
| 107 |
|
|||
| 137 | N-linked (GlcNAc...) asparagine |
|
||
| 195 | N-linked (GlcNAc...) asparagine | |||
| 214 | N-linked (GlcNAc...) asparagine | |||
| 303 | N-linked (GlcNAc...) asparagine | |||
| 316 | N-linked (GlcNAc...) asparagine |
|
||
| 371 | N-linked (GlcNAc...) asparagine |
|
||
| 397 | N-linked (GlcNAc...) asparagine |
|
G80920RR
G49108TO
G83460ZZ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
| Integrin cell surface interactions | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080202 | adenoid cystic carcinoma | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:11934 | head and neck cancer | |
| DOID:14261 | fragile X syndrome | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1749 | squamous cell carcinoma |
