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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Presenilin-1
Summary
- UniProt ID
- Q9W6T7
- Gene Symbol
-
- psen1
- Organism
- Danio rerio (zebrafish)
Annotation
- Keyword
-
- Cell membrane
- Cell projection
- Endoplasmic reticulum
- Golgi apparatus
- Notch signaling pathway
- Protease
- Reference proteome
- Synapse
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| membrane protein ectodomain proteolysis |
| amyloid-beta formation |
| swimming behavior |
| regulation of canonical Wnt signaling pathway |
| optomotor response |
| GO Term |
|---|
| gamma-secretase complex |
| mitochondrion |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| Golgi membrane |
| nucleus |
| Golgi apparatus |
| plasma membrane |
| membrane |
| axon |
| GO Term |
|---|
| cadherin binding |
| beta-catenin binding |
| aspartic endopeptidase activity, intramembrane cleaving |
Sequence
MADLVQNAANNVLNDGMDTSRHTSSTAAPPSRNEVELNGQPPTAPPPQVVTDSEEDEDEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTQKDGQQLIYTPFREDTETVGQRALHSMLNAIIMISVIVVMTLVLVVLYKYRCYKVIQAWLFFSNLLLLFFFSLIYLGEVFKTYNVAMDYFTLALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEAIFPALIYSSTMVWLFNMADSAETRNNSSHPVPQQENQVVAMAPTAQAEDDGGFTPAWVDHQQHQLGPMQSTEESRRQIQEMPSARPPPPADDDEERGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| EPH-ephrin mediated repulsion of cells | Danio rerio |
| Neutrophil degranulation | Danio rerio |
| Nuclear signaling by ERBB4 | Danio rerio |
| Regulated proteolysis of p75NTR | Danio rerio |
