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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Complement factor I
Summary
- UniProt ID
- Q9WUW3
- Gene Symbol
-
- Cfi
- If
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- Q9WUW3
Annotation
- Keyword
-
- Calcium
- Cleavage on pair of basic residues
- Complement pathway
- Disulfide bond
- Glycoprotein
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| complement activation |
| innate immune response |
| complement activation, classical pathway |
| cellular response to interleukin-6 |
| GO Term |
|---|
| extracellular space |
| membrane |
| GO Term |
|---|
| serine-type endopeptidase activity |
| metal ion binding |
Sequence
MKLALLILLLLNPHLSSSKNTPASGQPQEDLVEQKCLLKNYTHHSCDKVFCQPWQKCIEGTCACKLPYQCPKAGTPVCATNGRGYPTYCHLKSFECLHPEIKFSNNGTCTAEEKFNVSLIYGSTDTEGIVQVKLVDQDEKMFICKNSWSTVEANVACFDLGFPLGVRDIQGRFNIPVNHKINSTECLHVRCQGVETSLAECTFTKKSSKAPHGLAGVVCYTQDADFPTSQSFQCVNGKRIPQEKACDGVNDCGDQSDELCCKGCRGQAFLCKSGVCIPNQRKCNGEVDCITGEDESGCEEDKKNKIHKGLARSDQGGETEIETEETEMLTPDMDTERKRIKSLLPKLSCGVKRNTHIRRKRVVGGKPAEMGDYPWQVAIKDGDRITCGGIYIGGCWILTAAHCVRPSRYRNYQVWTSLLDWLKPNSQLAVQGVSRVVVHEKYNGATYQNDIALVEMKKHPGKKECELINSVPACVPWSPYLFQPNDRCIISGWGREKDNQKVYSLRWGEVDLIGNCSRFYPGRYYEKEMQCAGTSDGSIDACKGDSGGPLVCKDVNNVTYVWGIVSWGENCGKPEFPGVYTRVASYFDWISYYVGRPLVSQYNV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 40 | N-linked (GlcNAc...) asparagine |
|
||
| 106 | N-linked (GlcNAc...) asparagine |
|
||
| 116 | N-linked (GlcNAc...) asparagine |
|
||
| 182 | N-linked (GlcNAc...) asparagine |
|
||
| 515 | N-linked (GlcNAc...) asparagine |
|
||
| 557 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of Complement cascade | Rattus norvegicus |
