GlyCosmos Portal

Submissions

Tolloid-like protein 2

Summary

UniProt ID: Q9WVM6
Gene Symbol: Tll2
Gene ID: 24087
Organism: Mus musculus (house mouse)

External Links

Re-Glyco: Q9WVM6

Annotation

Keyword: Calcium Cleavage on pair of basic residues Developmental protein Differentiation Disulfide bond EGF-like domain Glycoprotein Metal-binding Metalloprotease Methylation Reference proteome Repeat Secreted Signal Zinc Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
dorsal/ventral pattern formation	IBA	GO_REF
protein processing	IBA	GO_REF
cell differentiation
negative regulation of skeletal muscle tissue growth	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

cellular developmental process [inference]

cell differentiation

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

dorsal/ventral pattern formation

developmental process [inference]

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of skeletal muscle tissue growth

regulation of developmental growth [inference]

regulation of skeletal muscle tissue growth [inference]

negative regulation of skeletal muscle tissue growth

negative regulation of developmental growth [inference]

negative regulation of skeletal muscle tissue growth

negative regulation of biological process [inference]

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of skeletal muscle tissue growth

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of skeletal muscle tissue growth

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of skeletal muscle tissue growth [inference]

negative regulation of skeletal muscle tissue growth

negative regulation of developmental growth [inference]

negative regulation of skeletal muscle tissue growth

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of skeletal muscle tissue growth

Displaying 1 entry
GO Term	Evidence Code	Reference
obsolete extracellular space

GO Hierarchy

cellular component

Displaying **all 4** entries
GO Term	Evidence Code	Reference
metalloendopeptidase activity	IBA	GO_REF
metalloendopeptidase activity	IEA	GO_REF
calcium ion binding	IEA	GO_REF
zinc ion binding	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPLATTLGTLVLLLLLPLPRGAEVTGDHSNVALDYGALEGEEGTEQQLHYHDPCKAAVFWGDIALDEDDLKLFHIDKAEDWTKPSIDKPGHDTGGLEETSARWPNDTASNASIQAPRKDGKDATTFLPNPGTSNTTAKTFSARVRRATTSRTERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIILNFTSMDLFKSRLCWYDYVEIRDGYWRKAPLLGRFCGDKIPESLVSSDSRLWVEFRSSSSSLGKGFFAVYEAMCGGDITKDAGQIQSPNYPDDYRPSKECVWRITVPDGFHVGLTFQSFEIERHDSCAYDYLEIRDGPTEDSTLIGHFCGYEKPEAVKSSANRLWVKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEQRCVNTLGSYTCACDPGYELAADKKTCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPVQYRISLQFEAFELEGNDVCKYDFVEVRSGLSPDAKLHGKFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQQECVNTFGSYLCRCRNGYRLHENGHDCKEAGCAYKISSAEGTLMSPNWPDKYPSRKECTWNISSTAGHRVKITFSEFEIEQHQECAYDHLELYDGTDSLAPILGRFCGSKKPDPVVATGSSLFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADCGYDFMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARYTSTKFQDALHMRK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
168	N-linked (GlcNAc...) asparagine	UniProt
358	N-linked (GlcNAc...) asparagine	UniProt
389	N-linked (GlcNAc...) asparagine	UniProt
625	N-linked (GlcNAc...) asparagine	UniProt
802	N-linked (GlcNAc...) asparagine	UniProt