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Clusterin

Summary

UniProt ID

Q9XSC5

Gene Symbol

ApoJ
CLU

Gene ID

100008713

Organism

Oryctolagus cuniculus (rabbit)

External Links

PubChem: Q9XSC5
Re-Glyco: Q9XSC5

Annotation

Keyword

Chaperone
Cytoplasm
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Membrane
Microsome
Mitochondrion
Nucleus
Phosphoprotein
Reference proteome
Secreted
Signal
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
extracellular space
nucleus
cytoplasm
mitochondrion
mitochondrial inner membrane
intracellular membrane-bounded organelle
cytosol
perinuclear region of cytoplasm
chromaffin granule
perinuclear endoplasmic reticulum lumen

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 15 in total

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GO Term
regulation of cell population proliferation
positive regulation of apoptotic process
positive regulation of NF-kappaB transcription factor activity
response to misfolded protein
protein stabilization
immune complex clearance
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of ubiquitin-dependent protein catabolic process
positive regulation of intrinsic apoptotic signaling pathway
negative regulation of protein-containing complex assembly

Displaying **all 3** entries
GO Term
ubiquitin protein ligase binding
misfolded protein binding
unfolded protein binding

Annotation information from UniProt.

Sequence

MKTLLLCVGLLLSWERGQVLGDQLVSDNELQEMSTQGSKYIDREIQNAVKGVQEIKTLIEKTNEERKTLLSVLEEAKKNKEDALNETRDSETKLKAFPEVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWINGDRIDSLLENDRQQSHVLDVMQDSFNRATGIMDELFQDRFFTHKPQDTFYHSPFSYFRRPPLHYAKSRLVRNIMPLSLYGPLNFQDMFQPFFEMIHQAQQAMDVHLHSPAYQTPNVEFITGGPDDRAVCKEIRHNSTGCLRMKDQCAKCQEILSVDCSANNPSQNQLRQELNDSLRLAEELTKRYNELLQSYQWKMLNTSSLLDQPNEQFNWVSQLANLTQGPDQYYLRVSTVTSHTSESEAPSRVTEVVVKLFDSDPITITIPEEVSRDNPKFMETVAEKALQEYRKKKRVE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
85	N-linked (GlcNAc...) asparagine	UniProt
102	N-linked (GlcNAc...) asparagine	UniProt
144	N-linked (GlcNAc...) asparagine	UniProt
289	N-linked (GlcNAc...) asparagine	UniProt
326	N-linked (GlcNAc...) asparagine	UniProt
352	N-linked (GlcNAc...) asparagine	UniProt
372	N-linked (GlcNAc...) asparagine	UniProt