Sialic acid-binding Ig-like lectin 7

Summary
UniProt ID
Q9Y286
Gene Symbol
  • SIGLEC7
  • AIRM1
Organism
Homo sapiens (human)
External Links
GlyConnect
GlyGen
Q9Y286
PubChem
Q9Y286
The Human Metabolome Database
HMDBP02570
The O-GlcNAc Database
Q9Y286
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell adhesion
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Lectin
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying 1 entry
GO Term
cell adhesion
Displaying 1 entry
GO Term
plasma membrane
Sequence
MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTSVSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK
Glycosylation Sites
Displaying all 9 entries
Position Description PubMed ID GlyTouCan ID Source
105 N-linked (GlcNAc...) asparagine
142 N-linked (GlcNAc...) asparagine
165 N-linked (GlcNAc...) asparagine
229 N-linked (GlcNAc...) asparagine
235 N-linked (GlcNAc...) asparagine
242 N-linked (GlcNAc...) asparagine
260 N-linked (GlcNAc...) asparagine
334 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Homo sapiens
Disease
Displaying entries 1 - 10 of 225 in total
DO ID Disease Name Source
DOID:0050539 Charcot-Marie-Tooth disease type 2
DOID:0050572 cone-rod dystrophy
DOID:0050635 alternating hemiplegia of childhood
DOID:0050782 Zollinger-Ellison syndrome
DOID:0050819 obsolete Matthew-Wood syndrome
DOID:0050865 tongue squamous cell carcinoma
DOID:0050902 medulloblastoma
DOID:0060262 gallbladder disease
DOID:0060597 atypical chronic myeloid leukemia, BCR-ABL1 negative
DOID:0060600 obsolete hereditary motor and sensory neuropathy with agenesis of the corpus callosum

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024