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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tyrosine--tRNA ligase, mitochondrial
Summary
- UniProt ID
- Q9Y2Z4
- Gene Symbol
-
- YARS2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Aminoacyl-tRNA synthetase
- Disease variant
- Mitochondrion
- Primary mitochondrial disease
- Protein biosynthesis
- Reference proteome
- Transit peptide
- Gene Ontology (GO)
| GO Term |
|---|
| translation |
| mitochondrial tyrosyl-tRNA aminoacylation |
| tRNA aminoacylation |
| GO Term |
|---|
| cytosol |
| mitochondrion |
| mitochondrial matrix |
| nuclear body |
| GO Term |
|---|
| tyrosine-tRNA ligase activity |
| RNA binding |
| ATP binding |
| protein homodimerization activity |
| tyrosine binding |
| tRNA binding |
Sequence
MAAPILRSFSWGRWSGTLNLSVLLPLGLRKAHSGAQGLLAAQKARGLFKDFFPETGTKIELPELFDRGTASFPQTIYCGFDPTADSLHVGHLLALLGLFHLQRAGHNVIALVGGATARLGDPSGRTKEREALETERVRANARALRLGLEALAANHQQLFTDGRSWGSFTVLDNSAWYQKQHLVDFLAAVGGHFRMGTLLSRQSVQLRLKSPEGMSLAEFFYQVLQAYDFYYLFQRYGCRVQLGGSDQLGNIMSGYEFINKLTGEDVFGITVPLITSTTGAKLGKSAGNAVWLNRDKTSPFELYQFFVRQPDDSVERYLKLFTFLPLPEIDHIMQLHVKEPERRGPQKRLAAEVTKLVHGREGLDSAKRCTQALYHSSIDALEVMSDQELKELFKEAPFSEFFLDPGTSVLDTCRKANAIPDGPRGYRMITEGGVSINHQQVTNPESVLIVGQHILKNGLSLLKIGKRNFYIIKWLQL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 354 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Mitochondrial tRNA aminoacylation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
