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Rap guanine nucleotide exchange factor 2

Summary

UniProt ID

Q9Y4G8

Gene Symbol

RAPGEF2
KIAA0313
NRAPGEP
PDZGEF1

Organism

Homo sapiens (human)

External Links

GlyGen: Q9Y4G8
PubChem: Q9Y4G8
The Human Metabolome Database: HMDBP01123
The O-GlcNAc Database: Q9Y4G8
O-GlcNAcAtlas: Q9Y4G8

Annotation

Keyword

3D-structure
Cell junction
Cell membrane
Cytoplasm
Developmental protein
Differentiation
Endosome
Epilepsy
GTPase activation
Guanine-nucleotide releasing factor
Neurogenesis
Phosphoprotein
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 37 in total

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GO Term
G protein-coupled receptor signaling pathway
neuropeptide signaling pathway
negative regulation of cell population proliferation
positive regulation of neuron projection development
ventricular system development
forebrain neuron development
microvillus assembly
neuron projection development
positive regulation of protein binding
intracellular signal transduction

Displaying entries **1 - 10** of 14 in total

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GO Term
membrane
endocytic vesicle
protein-containing complex
neuron projection
synapse
neuronal cell body
apical plasma membrane
cytosol
late endosome
perinuclear region of cytoplasm

Displaying **all 9** entries
GO Term
WW domain binding
diacylglycerol binding
PDZ domain binding
beta-1 adrenergic receptor binding
calcium ion binding
cAMP binding
guanyl-nucleotide exchange factor activity
GTPase activator activity
phosphatidic acid binding

Annotation information from UniProt.

Sequence

MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQVSAV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites