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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Epsin-1
Summary
- UniProt ID
- Q9Y6I3
- Gene Symbol
-
- EPN1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Coated pit
- Cytoplasm
- Endocytosis
- Lipid-binding
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| in utero embryonic development |
| endocytosis |
| female pregnancy |
| negative regulation of sprouting angiogenesis |
| embryonic organ development |
| Notch signaling pathway |
| GO Term |
|---|
| nucleus |
| plasma membrane |
| clathrin-coated pit |
| clathrin vesicle coat |
| cytosol |
| endosome |
| GO Term |
|---|
| molecular sequestering activity |
| clathrin binding |
| phospholipid binding |
Sequence
MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 420 |
|
|||
| 462 |
|
|||
| 517 |
|
|||
| 536 |
|
G49108TO
G43417UB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Homo sapiens |
| Clathrin-mediated endocytosis | Homo sapiens |
| EGFR downregulation | Homo sapiens |
