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Growth/differentiation factor 11

Summary

UniProt ID: Q9Z217
Gene Symbol: Gdf11 Bmp11
Gene ID: 29454
Organism: Rattus norvegicus (Norway rat)

External Links

Re-Glyco: Q9Z217

Annotation

Keyword: Cleavage on pair of basic residues Cytokine Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	Reference
skeletal system development	ISO	GO_REF
metanephros development	ISO	GO_REF
ureteric bud development	ISO	GO_REF
transforming growth factor beta receptor signaling pathway	IBA	GO_REF
cell population proliferation

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

cell population proliferation

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

amacrine cell differentiation

cell maturation [inference]

epithelial cell maturation [inference]

type B pancreatic cell maturation

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification

spinal cord anterior/posterior patterning

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

camera-type eye morphogenesis

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

epithelial cell maturation [inference]

type B pancreatic cell maturation

anatomical structure development [inference]

system development [inference]

skeletal system development

animal gross anatomical part developmental process [inference]

skeletal system development

tissue development [inference]

epithelium development [inference]

kidney epithelium development [inference]

mesonephric epithelium development [inference]

mesonephric tubule development [inference]

ureteric bud development

tube development [inference]

mesonephric tubule development [inference]

ureteric bud development

animal organ development [inference]

kidney development [inference]

metanephros development

pancreas development

roof of mouth development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

amacrine cell differentiation

cell maturation [inference]

epithelial cell maturation [inference]

type B pancreatic cell maturation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of amacrine cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of amacrine cell differentiation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of amacrine cell differentiation

regulation of neuron differentiation [inference]

negative regulation of neuron differentiation

negative regulation of amacrine cell differentiation

regulation of amacrine cell differentiation [inference]

negative regulation of amacrine cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of amacrine cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of amacrine cell differentiation

regulation of neuron differentiation [inference]

negative regulation of neuron differentiation

negative regulation of amacrine cell differentiation

regulation of amacrine cell differentiation [inference]

negative regulation of amacrine cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of amacrine cell differentiation

Displaying **all 3** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
protein-containing complex	ISO	GO_REF
protein-containing complex	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex

Displaying **all 2** entries
GO Term	Evidence Code	Reference
cytokine activity	IBA	GO_REF
growth factor activity	IEA	GO_REF

GO Hierarchy

molecular function

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MVLAAPLLLGFLLLALELRPRGEAAEGPAAAAAAAAAAAGVGGERSSRPAPSAAPEPDGCPVCVWRQHSRELRLESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETVISMAQETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQLWVYLRPVPRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSLKIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPFMELRVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites